Arterial hypertension is a significant cause of end-stage renal failure; effective treatment of hypertensive patients reduces the rate of progression of this disorder. β-Blockers, particularly nonselective agents, are associated with deterioration of renal function in patients with chronic renal failure. Previous studies on the interaction of the β 1-selective adrenergic antagonist bisoprolol with kidney function have been performed only acutely and over the short term. This study was designed to evaluate the antihypertensive efficacy and effects on renal hemodynamics and function of bisoprolol during medium-term (6 mo) treatment of patients with mild to moderate essential hypertension.
|Numero di pagine||11|
|Rivista||Advances in Therapy|
|Stato di pubblicazione||Published - 2007|
All Science Journal Classification (ASJC) codes
- Pharmacology (medical)
Paterna, S., Licata, G., Parrinello, G., Fasullo, S., Torres, D., Paterna, S., Di Pasquale, P., Fasullo, S., Tarantino, A., Torres, D., Fornaciari, E., & Antona, R. (2007). Medium-Term Effects ofBisoprolol Administrationon Renal Hemodynamics andFunction in Mild to ModerateEssential Hypertension. Advances in Therapy, 24, 1260-1270.