Medication-Related Osteonecrosis of Jaws (MRONJ) Prevention and Diagnosis: Italian Consensus Update 2020

Vera Panzarella, Rodolfo Mauceri, Antonio Lo Casto, Olga Di Fede, Giuseppina Campisi, Giordana Bettini, Vera Panzarella, Giacomo Oteri, Andrea Santarelli, Marco Mascitti, Olga Di Fede, Marco Meleti, Giuseppe Colella, Antonia Marcianò, Rodolfo Mauceri, Mario Gabriele, Lorenzo Lo Muzio, Giuseppina Campisi, Marco Mascitti, Umberto RomeoAlberto Bedogni, Matteo Biasotto, Ugo Consolo, Francesco Bertoldo, Antonio Lo Casto, Gianfranco Favia, Michele D. Mignogna, Paolo Vescovi, Claudio Marchetti, Vittorio Fusco

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46 Citazioni (Scopus)


The Medication-Related Osteonecrosis of Jaws (MRONJ) diagnosis process and its prevention play a role of great and rising importance, not only on the Quality of Life (QoL) of patients, but also on the decision-making process by the majority of dentists and oral surgeons involved in MRONJ prevention (primary and secondary). The present paper reports the update of the conclusions from the Consensus Conference-held at the Symposium of the Italian Society of Oral Pathology and Medicine (SIPMO) (20 October 2018, Ancona, Italy)-after the newest recommendations (2020) on MRONJ were published by two scientific societies (Italian Societies of Maxillofacial Surgery and Oral Pathology and Medicine, SICMF and SIPMO), written on the inputs of the experts of the Italian Allied Committee on ONJ (IAC-ONJ). The conference focused on the topic of MRONJ, and in particular on the common practices at risk of inappropriateness in MRONJ diagnosis and therapy, as well as on MRONJ prevention and the dental management of patients at risk of MRONJ. It is a matter of cancer and osteometabolic patients that are at risk since being exposed to several drugs with antiresorptive (i.e., bisphosphonates and denosumab) or, more recently, antiangiogenic activities. At the same time, the Conference traced for dentists and oral surgeons some easy applicable indications and procedures to reduce MRONJ onset risk and to diagnose it early. Continuous updating on these issues, so important for the patient community, is recommended.
Lingua originaleEnglish
Numero di pagine15
RivistaInternational Journal of Environmental Research and Public Health
Stato di pubblicazionePublished - 2020

All Science Journal Classification (ASJC) codes

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