The “stem cells” discipline represents one of the most dynamic areas in biomedicine.While adult marine/aquatic invertebrate stem cell (MISC) biology is of prime research and medicalinterest, studies on stem cells from organisms outside the classical vertebrate (e.g., human, mouse,and zebrafish) and invertebrate (e.g., Drosophila, Caenorhabditis) models have not been pursuedvigorously. Marine/aquatic invertebrates constitute the largest biodiversity and the widestphylogenetic radiation on Earth, from morphologically simple organisms (e.g., sponges,cnidarians), to the more complex mollusks, crustaceans, echinoderms, and protochordates. Theseorganisms contain a kaleidoscope of MISC-types that allow the production of a large number ofnovel bioactive-molecules, many of which are of significant potential interest for human health.MISCs further participate in aging and regeneration phenomena, including whole-bodyregeneration. For years, the European MISC-community has been highly fragmented and hasestablished scarce ties with biomedical industries in an attempt to harness MISCs for humanwelfare. Thus, it is important to (i) consolidate the European community of researchers working onMISCs; (ii) promote and coordinate European research on MISC biology; (iii) stimulate youngresearchers to embark on research in MISC-biology; (iv) develop, validate, and share novel MISCtools and methodologies; (v) establish the MISC discipline as a forefront interest of biomedicaldisciplines, including nanobiomedicine; and vi) establish collaborations with industries to exploitMISCs as sources of bioactive molecules. In order to fill the recognized gaps, the EC-COST Action16203 “MARISTEM” has recently been launched. At its initial stage, the consortium unites 26scientists from EC countries, Cooperating countries, and Near Neighbor Countries.
|Numero di pagine||21|
|Stato di pubblicazione||Published - 2018|