Management of laryngeal precancerous lesions

Francesco Martines, Carlo Dispenza, Alessandro De Stefano, Donatella Marchese, Francesco Dispenza

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11 Citazioni (Scopus)

Abstract

Objective: The identification of precancerous lesions is the basis of an early diagnosis, and of a treatment that allows, in the great part of cases, the preservation of organ functions. The aims of this study were: the evaluation of the less invasive treatment for precancerous lesion of the larynx to minimize the recurrences, the estimation of number of further operation required. Methods: A prospective study was clone on patients with clinical diagnosis of laryngeal precancerosis. The patients were treated by a transoral endoscopic approach with direct microlaryngoscopy (DML) doing an excision-biopsy with cold blade, consisting in excision of the whole visible lesion with vocal ligament preservation. Results: A recurrence of a clinically evident precancerous lesion was present in 13.2% of patients that had a laryngeal intraepithelial lesion (LIN) 1 lesion and in 28.95% of patients that had a LIN 2 lesion. Conclusion: In order to achieve a control of a precancerous lesion, we suggest: excisional biopsy/subepithelial cordectomy (type 1 cordectomy) for LIN 1 lesions and subligament cordectomy (type 2 cordectomy) in case of LIN 2 cases. In case of recurrences of LIN 1 lesion we suggest directly a type 2 cordectomy.
Lingua originaleEnglish
pagine (da-a)280-283
Numero di pagine4
RivistaAURIS, NASUS, LARYNX
Volume39
Stato di pubblicazionePublished - 2012

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology

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    Martines, F., Dispenza, C., De Stefano, A., Marchese, D., & Dispenza, F. (2012). Management of laryngeal precancerous lesions. AURIS, NASUS, LARYNX, 39, 280-283.