Management of Intra-abdominal Infections due to Carbapenemase-Producing Organisms.

Francesco Vitale, Alessandra Casuccio, Paola Di Carlo, Criostóir Ó’Súilleabháin, Criostóir Ó’Súilleabháin

Risultato della ricerca: Articlepeer review

11 Citazioni (Scopus)


The prevalence of bacterial resistance to carbapenem antibiotics continues to increase because of bacteria producing metallo-β-lactamases (MBL), called carbapenemase-producing organisms (CPO). Enterobacteriaceae, which can be a common cause of intra-abdominal infections (IAIs), have become carbapenem-resistant Enterobacteriaceae (CRE). Updated international guidelines for the treatment of both IAIs and IAIs due to CRE have been published. Given the multifaceted nature of these infections, these recommendations have been jointly reviewed and endorsed by the Surgical Society and the Association of Medical Microbiology and Infectious Disease. The aims of this review are to summarize the general and new generation of multimodal procedure to manage IAIs due to CRE and review the data available on the combination of interventions to reduce CRE. Future research should focus on the development of novel and safe antimicrobial therapies and the quantification of the incremental effect of infection control programmes and new methods to rapidly detect pathogens before patients enter the surgical setting
Lingua originaleEnglish
pagine (da-a)428-437
Numero di pagine10
RivistaCurrent Infectious Disease Reports
Stato di pubblicazionePublished - 2014

All Science Journal Classification (ASJC) codes

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