Liraglutide decreases carotid intima-media thickness in patients with type 2 diabetes: 8-month prospective pilot study.

Giuseppe Montalto, Manfredi Rizzo, Angelo Maria Patti, Manisha Chandalia, Nicola Abate, Ali A. Rizvi, Manfredi Rizzo

    Risultato della ricerca: Articlepeer review

    62 Citazioni (Scopus)

    Abstract

    BACKGROUND: Liraglutide, a long-acting glucagon-like peptide-1 (GLP-1) analog, has several non- glycemic properties, but its effect on carotid intima-media thickness (IMT), a recognized marker of subclinical atherosclerosis, is still unknown. METHODS: A prospective study of 8 months duration in 64 patients with type-2 diabetes and no prior history of coronary artery disease evaluated whether adding liraglutide to metformin affects carotid IMT, measured by color doppler ultrasound. RESULTS: After 8 months, fasting glucose decreased by 2.1 mmol/l and HbA1c by 1.9% (p 
    Lingua originaleEnglish
    pagine (da-a)49-
    Numero di pagine5
    RivistaCardiovascular Diabetology
    Volume13
    Stato di pubblicazionePublished - 2014

    All Science Journal Classification (ASJC) codes

    • Endocrinology, Diabetes and Metabolism
    • Cardiology and Cardiovascular Medicine

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