Several acyl derivatives of cnicin were obtained through lipase-catalysed acylation and alcoholysis reactions.In most reactions lipases showed a regioselective behaviour affording only one product. Longerchain acyl derivatives were prepared at lower temperature than the used in lipase-catalysed reactions, topreclude side products formation. The enzymatic approach let to prepare a family of novel acetyl and fattyacid derivatives of cnicin which are not obtainable following traditional organic synthetic procedures.
|Numero di pagine||8|
|Rivista||JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC|
|Stato di pubblicazione||Published - 2009|
All Science Journal Classification (ASJC) codes
- Process Chemistry and Technology
Rosselli, S., Bruno, M., Monsalve, L. N., & Baldessari, A. (2009). Lipase-catalysed preparation of acyl derivatives of the germacranolide sesquiterpenoid cnicin. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 57, 40-47.