TY - JOUR
T1 - Left ventricular hypertrophy or storage disease? the incremental value of speckle tracking strain bull's-eye
AU - Novo, Giuseppina
AU - Esposito, Roberta
AU - Rossi, Andrea
AU - Cameli, Matteo
AU - Bossone, Eduardo
AU - Radmilovic, Juri
AU - D'Andrea, Antonello
AU - Novo, Giuseppina
AU - Montisci, Roberta
AU - Mondillo, Sergio
AU - Agricola, Eustachio
AU - Gallina, Sabina
AU - Galderisi, Maurizio
AU - Mele, Donato
AU - Ballo, Piercarlo
PY - 2017
Y1 - 2017
N2 - Left ventricular hypertrophy (LVH) develops in response to a variety of physical, genetic, and biochemical stimuli and represents the early stage of ventricular remodeling. In patients with LVH, subclinical left ventricular (LV) dysfunction despite normal ejection fraction (EF) may be present before the onset of symptoms, which portends a dismal prognosis. Strain measurement with two-dimensional speckle tracking echocardiography (STE) represents a highly reproducible and accurate alternative to LVEF determination. The present review focuses on current available evidence that supports the incremental value of STE in the diagnostic and prognostic workup of LVH. When assessing the components of LV contraction, STE has an incremental value in differentiating between primary and secondary LVH and in the differential diagnosis with storage diseases. In addition, STE provides unique information for the stratification of patients with LVH, enabling to detect intrinsic myocardial dysfunction before LVEF reduction.
AB - Left ventricular hypertrophy (LVH) develops in response to a variety of physical, genetic, and biochemical stimuli and represents the early stage of ventricular remodeling. In patients with LVH, subclinical left ventricular (LV) dysfunction despite normal ejection fraction (EF) may be present before the onset of symptoms, which portends a dismal prognosis. Strain measurement with two-dimensional speckle tracking echocardiography (STE) represents a highly reproducible and accurate alternative to LVEF determination. The present review focuses on current available evidence that supports the incremental value of STE in the diagnostic and prognostic workup of LVH. When assessing the components of LV contraction, STE has an incremental value in differentiating between primary and secondary LVH and in the differential diagnosis with storage diseases. In addition, STE provides unique information for the stratification of patients with LVH, enabling to detect intrinsic myocardial dysfunction before LVEF reduction.
KW - Nuclear Medicine and Imaging; Cardiology and Cardiovascular Medicine
KW - amyloidosis; anabolic steroids; aortic stenosis; arterial hypertension; athlete's heart; hypertrophic cardiomyopathy; left ventricular hypertrophy; speckle tracking echocardiography; two-dimensional strain; Radiology
KW - Nuclear Medicine and Imaging; Cardiology and Cardiovascular Medicine
KW - amyloidosis; anabolic steroids; aortic stenosis; arterial hypertension; athlete's heart; hypertrophic cardiomyopathy; left ventricular hypertrophy; speckle tracking echocardiography; two-dimensional strain; Radiology
UR - http://hdl.handle.net/10447/238323
UR - http://www.wiley.com/bw/journal.asp?ref=0742-2822&site=1
M3 - Article
VL - 34
SP - 746
EP - 759
JO - Echocardiography
JF - Echocardiography
SN - 0742-2822
ER -