LEFT VENTRICULAR HYPERTROPHY IN HYPERTENSIVEPATIENTS WITH NORMAL ELECTROCARDIOGRAM

Giovanni Cerasola, Paola Cusimano, Giuseppe Mule', Emilio Nardi, Alessandro Palermo, Giovanna Bonanno, Miriam Costanzo

Risultato della ricerca: Other

Abstract

Objective: In hypertensive patients the presence of left ventricular hypertrophy(LVH) is associated with increased cardiovascular (CV) morbidity and mortality.Unfortunately electrocardiogram (ECG) has a low sensitivity in detecting LVH,while echocardiography cannot be routinely and extensively performed in allhypertensive patients. In this study we evaluated the prevalence of LVH and ofanomalies of diastolic function in a group of hypertensive patients with normalECG, and free of diabetes and CV diseases.Design and Methods: Patients with CV diseases, diabetes, chronic kidney disease(CKD), electrocardiographic LVH (Sokolow-Lyons or Cornell criterion) or“strain” were excluded. We enrolled 196 middle-aged hypertensive patients (M/F:124/72). All the enrolled subjects underwent an echocardiographic examination(Acuson Sequoia 512). Left ventricular mass (LVM) was indexed by body surfacearea (LVMI) and by height2.7 (LVMH2.7). LVH was defined as LVMI >125g/m2 inmen and >110 g/m2 in women, or as LVMH2.7 >51 g/m2.7 in both sexes. Diastolicfunction was principally assessed by Tissue Doppler Imaging (TDI).Results: With regard to LVMI, 20/196 patients (10.2%) had LVH (2 eccentricand e 18 concentric, 12 women and 8 men). In this subgroup of 20 subjects,the value of LVMI had a percentage difference from the cut-off value for LVHof 15.1 ± 11.4%. Among the 196 patients, only 6 out of the 20 with LVH had diastolic dysfunction, defined as early diastolic myocardial velocity (Em)<0.08 m/s.Conclusions: The prevalence of LVH among hypertensive patients with normal ECG, free of diabetes and of CVdiseases is low; moreover, patients with echocardiographic LVH presented LVMI values that identified mild LVH. Fewcases of impaired diastolic function were registered.We suggest that in hypertensive patients with such characteristics the echocardiographic examination should be reserved to those who present with higher duration of hypertension.
Lingua originaleEnglish
Pagine127-127
Numero di pagine1
Stato di pubblicazionePublished - 2011

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