Lapatinib activity in a patient with encephalic metastases from trastuzumab-resistant her-2 positive breast cancer

Calogero Cipolla, Maria Rosaria Valerio, Giuseppa Graceffa, Daniele Galanti, Giovanni Vaccaro

Risultato della ricerca: Articlepeer review


A 42-year-old woman with right breast cancer cT4dN2M0 HR +, HER2 +, undergoes mastectomy with axillary lymphadenectomy after neoadjuvant chemotherapy. During adjuvant treatment with trastuzumab and hormone therapy, the patient develops multiple symptomatic encephalic metastases. She undergoes panencephalic radiotherapy and begins chemotherapy with capecitabine and lapatinib. After three months of well tolerated therapy, an important volumetric response of encephalic metastases is observed, with regression of neurological symptoms.
Lingua originaleEnglish
pagine (da-a)2985-2987
Numero di pagine3
RivistaActa Medica Mediterranea
Stato di pubblicazionePublished - 2020

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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