Laparoscopic radical hysterectomy in cervical cancer as total mesometrial resection (L-TMMR): A multicentric experience

Vito Chiantera, Petrillo, Giuseppe Vizzielli, Lucidi, Muallem, Scambia, Legge, Vito Chiantera, Sehouli, Anna Fagotti, Giovanni Scambia, Valerio Gallotta

Risultato della ricerca: Articlepeer review

17 Citazioni (Scopus)


Objective To analyze the feasibility of total mesometrial resection by laparoscopy (L-TMMR) in a multicentric series of early stage cervical cancer. Method We prospectively evaluated a consecutive series of cervical cancer patients with pre-operative FIGO stages IA2-IB1 at the Catholic University in Rome and in Campobasso and the Charitè University in Berlin. All cases were assessed at pre-operative MRI scan and clinically confirmed by investigation under anesthesia, adhering strictly to the FIGO criteria. The surgical and post-surgical data were collected. Results 104 women with cervical cancer were admitted between July 2013 and August 2014 and among them 71 patients with pre-operative FIGO stages IA2-IB1 were treated with L-TMMR. One laparotomic conversion was registered. The median operative time was 260 min (120-670 min), estimated blood loss was 100 cm3 (25-900 cm3), and the median length of hospital stay was 6 days (2-26 days). We observed 8 intra-operative complications including a vascular injury of the left internal iliac vein that caused conversion, 6 vesical injuries and 1 ureteral injury managed laparoscopically. Two vescico-vaginal fistula and one hemoperitoneum were observed as major post-operative complications (4.2%). Conclusion L-TMMR can be safely performed in selected cervical cancer patients. Further larger prospective trials are needed to evaluate the oncological outcome of patients undergoing this surgical procedure.
Lingua originaleEnglish
pagine (da-a)47-51
Numero di pagine5
RivistaGynecologic Oncology
Stato di pubblicazionePublished - 2015

All Science Journal Classification (ASJC) codes

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