La terapia chirurgica del morbo di Basedow. Tiroidectomia totale o subtotale a confronto

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Abstract

The surgical treatment of Basedow's disease is the most rapid and effective therapeutic approach to obtain the long-term remission of disease. Controversy persists regarding the choice of total or subtotal thyroidectomy. The authors report their experience in 38 cases of Basedow's disease undergoing surgery, of which 20 were treated with total thyroidectomy and 18 with subtotal thyroidectomy. No hemorrhages, wound infections, recurrent lesions, or definitive hypoparathyroidism were observed in the two groups of patients. Those patients undergoing subtotal thyroidectomy reported a 44.5% incidence of hypothyroidism. In particular, hypothyroidism was clinically manifest in 16.7% of cases and subclinical in 27.8%, namely only revealed by the assay of thyroid hormones. Relapse of hyperthyroidism was also reported in 16.7% of the cases treated by subtotal thyroidectomy. On the basis of these results and owing to the high incidence of hypothyroidism and the relatively high percentage of recurrent hyperthyroidism after subtotal thyroidectomy, the authors conclude that total thyroidectomy may be considered the surgical treatment of choice in Basedow's disease in that there were no major complications following this type of surgery compared to subtotal thyroidectomy. Moreover, total thyroidectomy eliminates the risk of recurrent hyperthyroidism and therefore the need to re-operate, and also ensures the removal of possible foci of occult carcinoma reported in 5-10% of cases.
Lingua originaleItalian
pagine (da-a)225-230
Numero di pagine6
RivistaCHIRURGIA
Volume9
Stato di pubblicazionePublished - 1996

All Science Journal Classification (ASJC) codes

  • Surgery

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title = "La terapia chirurgica del morbo di Basedow. Tiroidectomia totale o subtotale a confronto",
abstract = "The surgical treatment of Basedow's disease is the most rapid and effective therapeutic approach to obtain the long-term remission of disease. Controversy persists regarding the choice of total or subtotal thyroidectomy. The authors report their experience in 38 cases of Basedow's disease undergoing surgery, of which 20 were treated with total thyroidectomy and 18 with subtotal thyroidectomy. No hemorrhages, wound infections, recurrent lesions, or definitive hypoparathyroidism were observed in the two groups of patients. Those patients undergoing subtotal thyroidectomy reported a 44.5{\%} incidence of hypothyroidism. In particular, hypothyroidism was clinically manifest in 16.7{\%} of cases and subclinical in 27.8{\%}, namely only revealed by the assay of thyroid hormones. Relapse of hyperthyroidism was also reported in 16.7{\%} of the cases treated by subtotal thyroidectomy. On the basis of these results and owing to the high incidence of hypothyroidism and the relatively high percentage of recurrent hyperthyroidism after subtotal thyroidectomy, the authors conclude that total thyroidectomy may be considered the surgical treatment of choice in Basedow's disease in that there were no major complications following this type of surgery compared to subtotal thyroidectomy. Moreover, total thyroidectomy eliminates the risk of recurrent hyperthyroidism and therefore the need to re-operate, and also ensures the removal of possible foci of occult carcinoma reported in 5-10{\%} of cases.",
author = "Giuseppa Graceffa and Gianni Pantuso and Mario Latteri and Calogero Cipolla",
year = "1996",
language = "Italian",
volume = "9",
pages = "225--230",
journal = "CHIRURGIA",
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TY - JOUR

T1 - La terapia chirurgica del morbo di Basedow. Tiroidectomia totale o subtotale a confronto

AU - Graceffa, Giuseppa

AU - Pantuso, Gianni

AU - Latteri, Mario

AU - Cipolla, Calogero

PY - 1996

Y1 - 1996

N2 - The surgical treatment of Basedow's disease is the most rapid and effective therapeutic approach to obtain the long-term remission of disease. Controversy persists regarding the choice of total or subtotal thyroidectomy. The authors report their experience in 38 cases of Basedow's disease undergoing surgery, of which 20 were treated with total thyroidectomy and 18 with subtotal thyroidectomy. No hemorrhages, wound infections, recurrent lesions, or definitive hypoparathyroidism were observed in the two groups of patients. Those patients undergoing subtotal thyroidectomy reported a 44.5% incidence of hypothyroidism. In particular, hypothyroidism was clinically manifest in 16.7% of cases and subclinical in 27.8%, namely only revealed by the assay of thyroid hormones. Relapse of hyperthyroidism was also reported in 16.7% of the cases treated by subtotal thyroidectomy. On the basis of these results and owing to the high incidence of hypothyroidism and the relatively high percentage of recurrent hyperthyroidism after subtotal thyroidectomy, the authors conclude that total thyroidectomy may be considered the surgical treatment of choice in Basedow's disease in that there were no major complications following this type of surgery compared to subtotal thyroidectomy. Moreover, total thyroidectomy eliminates the risk of recurrent hyperthyroidism and therefore the need to re-operate, and also ensures the removal of possible foci of occult carcinoma reported in 5-10% of cases.

AB - The surgical treatment of Basedow's disease is the most rapid and effective therapeutic approach to obtain the long-term remission of disease. Controversy persists regarding the choice of total or subtotal thyroidectomy. The authors report their experience in 38 cases of Basedow's disease undergoing surgery, of which 20 were treated with total thyroidectomy and 18 with subtotal thyroidectomy. No hemorrhages, wound infections, recurrent lesions, or definitive hypoparathyroidism were observed in the two groups of patients. Those patients undergoing subtotal thyroidectomy reported a 44.5% incidence of hypothyroidism. In particular, hypothyroidism was clinically manifest in 16.7% of cases and subclinical in 27.8%, namely only revealed by the assay of thyroid hormones. Relapse of hyperthyroidism was also reported in 16.7% of the cases treated by subtotal thyroidectomy. On the basis of these results and owing to the high incidence of hypothyroidism and the relatively high percentage of recurrent hyperthyroidism after subtotal thyroidectomy, the authors conclude that total thyroidectomy may be considered the surgical treatment of choice in Basedow's disease in that there were no major complications following this type of surgery compared to subtotal thyroidectomy. Moreover, total thyroidectomy eliminates the risk of recurrent hyperthyroidism and therefore the need to re-operate, and also ensures the removal of possible foci of occult carcinoma reported in 5-10% of cases.

UR - http://hdl.handle.net/10447/217147

M3 - Article

VL - 9

SP - 225

EP - 230

JO - CHIRURGIA

JF - CHIRURGIA

SN - 0394-9508

ER -