Is it possible to make a diagnosis of raw, heated and baked egg allergy in children using cut-offs? A systematic review

Stefania La Grutta; Giovanni Cosimo Indirli; Arianna Dondi; Stefania Arasi; Maria Carmen Verga; Barbara Cuomo; Annamaria Bianchi; Valentina Panetta; Stefania La Grutta; Mauro Calvani; Davide Caimmi

Is it possible to make a diagnosis of raw, heated and baked egg allergy in children using cut-offs? A systematic review

Stefania La Grutta, Giovanni Cosimo Indirli, Arianna Dondi, Stefania Arasi, Maria Carmen Verga, Barbara Cuomo, Annamaria Bianchi, Valentina Panetta, Stefania La Grutta, Mauro Calvani, Davide Caimmi

Risultato della ricerca: Article › peer review

38 Citazioni (Scopus)

Abstract

The diagnosis of IgE-mediated egg allergy lies both on a compatible clinical history and on the results of skin prick tests (SPTs) and IgEs levels. Both tests have good sensitivity but low specificity. For this reason, oral food challenge (OFC) is the ultimate gold standard for the diagnosis. The aim of the present paper is to systematically review the literature in order to identify, analyze and synthesize the predictive value of SPT and specific IgEs both to egg white and main egg allergens and to review the cut-offs suggested in the literature.

Lingua originale	English
pagine (da-a)	509-521
Numero di pagine	13
Rivista	Pediatric Allergy and Immunology
Stato di pubblicazione	Published - 2015

All Science Journal Classification (ASJC) codes

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title = "Is it possible to make a diagnosis of raw, heated and baked egg allergy in children using cut-offs? A systematic review",

abstract = "The diagnosis of IgE-mediated egg allergy lies both on a compatible clinical history and on the results of skin prick tests (SPTs) and IgEs levels. Both tests have good sensitivity but low specificity. For this reason, oral food challenge (OFC) is the ultimate gold standard for the diagnosis. The aim of the present paper is to systematically review the literature in order to identify, analyze and synthesize the predictive value of SPT and specific IgEs both to egg white and main egg allergens and to review the cut-offs suggested in the literature.",

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author = "{La Grutta}, Stefania and Indirli, {Giovanni Cosimo} and Arianna Dondi and Stefania Arasi and Verga, {Maria Carmen} and Barbara Cuomo and Annamaria Bianchi and Valentina Panetta and {La Grutta}, Stefania and Mauro Calvani and Davide Caimmi",

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T1 - Is it possible to make a diagnosis of raw, heated and baked egg allergy in children using cut-offs? A systematic review

AU - La Grutta, Stefania

AU - Indirli, Giovanni Cosimo

AU - Dondi, Arianna

AU - Arasi, Stefania

AU - Verga, Maria Carmen

AU - Cuomo, Barbara

AU - Bianchi, Annamaria

AU - Panetta, Valentina

AU - La Grutta, Stefania

AU - Calvani, Mauro

AU - Caimmi, Davide

PY - 2015

Y1 - 2015

N2 - The diagnosis of IgE-mediated egg allergy lies both on a compatible clinical history and on the results of skin prick tests (SPTs) and IgEs levels. Both tests have good sensitivity but low specificity. For this reason, oral food challenge (OFC) is the ultimate gold standard for the diagnosis. The aim of the present paper is to systematically review the literature in order to identify, analyze and synthesize the predictive value of SPT and specific IgEs both to egg white and main egg allergens and to review the cut-offs suggested in the literature.

AB - The diagnosis of IgE-mediated egg allergy lies both on a compatible clinical history and on the results of skin prick tests (SPTs) and IgEs levels. Both tests have good sensitivity but low specificity. For this reason, oral food challenge (OFC) is the ultimate gold standard for the diagnosis. The aim of the present paper is to systematically review the literature in order to identify, analyze and synthesize the predictive value of SPT and specific IgEs both to egg white and main egg allergens and to review the cut-offs suggested in the literature.

KW - cut-off

KW - egg

KW - oral food challenge

KW - skin prick test

KW - specific IgE

KW - cut-off

KW - egg

KW - oral food challenge

KW - skin prick test

KW - specific IgE

UR - http://hdl.handle.net/10447/143352

UR - http://www.ncbi.nlm.nih.gov/pubmed/26102461

M3 - Article

SP - 509

EP - 521

JO - Pediatric Allergy and Immunology

JF - Pediatric Allergy and Immunology

SN - 0905-6157

ER -

Is it possible to make a diagnosis of raw, heated and baked egg allergy in children using cut-offs? A systematic review

Abstract

All Science Journal Classification (ASJC) codes

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