Investigating the Antiproliferative and Antioxidant Properties of Pancratium maritimum L. (Amaryllidaceae) Stems, Flowers, Bulbs, and Fruits Extracts

Maurizio Bruno, Mariarosaria Leporini, Tiziana Falco, Rosa Tundis, Monica R. Loizzo

Risultato della ricerca: Article

1 Citazioni (Scopus)

Abstract

Pancratium maritimum stems, flowers, bulbs, and fruits extracts were investigated for their antiproliferative and antioxidant properties. Total phenols and total flavonoids were also determined. The in vitro antiproliferative activity was tested against seven cancer cell lines such as C32, HeLa, MDA-MB-231, PC3, A549, MCF-7, and LNCaP by using SRB assay. Interesting results were obtained with stems ethanol extract (ET1) against C32 cells (IC50 of 27.1 μg/mL) and fruits aqueous extract (AQ) against MCF-7 cell line (IC50 of 36.5 μg/mL). To define the antioxidant activity, four tests such as DPPH, ABTS FRAP, and β-carotene bleaching tests were used. The most promising ABTS scavenging capacity was observed with fruits ethanol extract (ET1) that showed an IC50 value of 6.9 μg/mL. According to the correlation results, the phenols and flavonoids content could provide a fundamental contribution to the antioxidant and antiproliferative activity of P. maritimum extracts.
Lingua originaleEnglish
pagine (da-a)1-7
Numero di pagine7
RivistaEvidence-based Complementary and Alternative Medicine
Volume2018
Stato di pubblicazionePublished - 2018

All Science Journal Classification (ASJC) codes

  • Complementary and alternative medicine

Fingerprint Entra nei temi di ricerca di 'Investigating the Antiproliferative and Antioxidant Properties of Pancratium maritimum L. (Amaryllidaceae) Stems, Flowers, Bulbs, and Fruits Extracts'. Insieme formano una fingerprint unica.

  • Cita questo