Internalizing symptoms in children affected by childhood absence epilepsy: A preliminary study

Lucia Parisi, Agata Maltese, Michele Roccella, Margherita Salerno, Giovanni Messina, Maria Ruberto, Francesco Precenzano, Paola Lombardi, Ilaria D'Alessandro, Rosaria Martina Magliulo, Immacolata Della Valle, Giovanni Messina

Risultato della ricerca: Articlepeer review

48 Citazioni (Scopus)


Introduction: Childhood absence epilepsy (CAE) is a common type of pediatric idiopathic generalized epilepsy, characterized by multiple seizures of typical absence, with typical EEG pattern consisting in bilateral synchronous and symmetrical discharges of generalized 3 Hz spike-wave (SWDs). Recently, some researchers have suggested that the underlying epileptogenic mechanism of absence seizures selectively involves the frontal cortical circuits, also supported by video-electroencephalography data(3). These data may be considered as a new window in CAE comprehension and management, particularly about symptoms different from seizure that children affected may present. In this light, aim of the present study is evaluating the presence of internalizing problems in prepubertal children affected by CAE. Material and methods: 18 patients (10 females, 8 males) ranging age from 8-11 years (mean age 9.36 ± 1.32) affected by typical CAE were recruited. Control group was composed by 43 subjects (32 females, 11 males) (mean age 8.54 ± 2.01). All subjects were screened for internalizing symptoms with SAFA-A scale and CDI test. Results: The two groups were comparable for age (p=0.117) and sex distribution (p=0.251). CAE children showed significantly higher score than controls for anxiety (p<0.001) and depressive symptoms screening tests (p<0.001) (Table 1). Conclusions: Results of present study suggest the importance of screening for anxiety and depressive signs in CAE children, in order to optimize their management beyond the exclusive idea to control and stop epileptic seizure only.
Lingua originaleEnglish
pagine (da-a)1749-1753
Numero di pagine5
RivistaActa Medica Mediterranea
Stato di pubblicazionePublished - 2016

All Science Journal Classification (ASJC) codes

  • ???subjectarea.asjc.2700.2700???


Entra nei temi di ricerca di 'Internalizing symptoms in children affected by childhood absence epilepsy: A preliminary study'. Insieme formano una fingerprint unica.

Cita questo