Insights from experiences on antiplatelet drugs in stroke prevention: A review

Domenico Di Raimondo, Marco Mangiafico, Salvatore Davide Tomasello, Ingrid Platania, Salvatore Santo Signorelli, Giuliana Barcellona, Agostino Gaudio, Giuseppe Barcellona

Risultato della ricerca: Articlepeer review

Abstract

Reduction of hazard risk of cerebral ischemic event (stroke, transient ischemic attack (TIA)) represents the hard point to be achieved from primary or secondary preventive strategy in the best clinical practice. However, results from clinical trials, recommendations, guidelines, systematic review, expert opinions, and meta-analysis debated on the optimal pharmacotherapy to achieve the objective. Aspirin and a number of antiplatelet agents, alone or in combination, have been considered from large trials focused on stroke prevention. The present review summarizes, discusses results from trials, and focuses on the benefits or disadvantages originating from antiplatelet drugs. Sections of the review were organized to show both benefits or consequences from antiplatelet pharmacotherapy. Conclusively, this review provides a potential synopsis on the most appropriate therapeutic approach for stroke prevention in clinical practice.
Lingua originaleEnglish
pagine (da-a)1-15
Numero di pagine15
RivistaInternational Journal of Environmental Research and Public Health
Volume17
Stato di pubblicazionePublished - 2020

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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