Inhibition of glial proliferation in vitro by serum from patients with multiple sclerosis

Risultato della ricerca: Articlepeer review

2 Citazioni (Scopus)

Abstract

Primary cell cultures from fetal rat CNS have been employed to evaluate the effects caused by the addition of serum from patients affected by multiple sclerosis (MS). MS-serum supplemented media caused a decrease in [3H]-thymidine incorporation into the cultures, thus indicating an inhibitory effect on proliferating glial cells. Sera from patients in remission stage of the disease showed an inhibitory effect not significatively lower than those from patients in acute stage. These results suggest that glial cells may be a target of circulating factors present in MS.
Lingua originaleEnglish
pagine (da-a)237-240
Numero di pagine4
RivistaActa Neurologica Scandinavica
Volume76
Stato di pubblicazionePublished - 1987

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

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