INFLAMMATORY BOWEL DISEASE AND COLORECTAL CANCER, NUTRACEUTICAL ASPECTS

Giovanni Tomasello, Francesco Carini, Angelo Leone, Francesca Rappa, Rosalyn Jurjus, Tarek Bou Assi, Francesca Rappa, Alice Gerges Geagea, Eleonora Trovato, Giovanni Tomasello, Tarek Bou Assi, Tarek Bou Assi, Abdo Jurjus

Risultato della ricerca: Article

7 Citazioni (Scopus)

Abstract

Nutraceuticals constitute a group of functional foods that provide added health benefits for various disorders including inflammatory bowel disease (IBD) and colorectal cancer (CCR). The main groups of nutraceuticals include probiotics, prebiotics omega 3 and antioxidants. Studies on nutraceutical showed that this type of food possessed similar properties to drugs but with the benefit of not having side effects. This mini review shows that probiotics and prebiotics, when administered simultaneously with traditional therapies, reduce IBD symptoms and reduce synthesis of enzymes probably involved in colorectal carcinogenesis. Moreover, Omega 3 reduces the synthesis of inflammation mediators and prevenents carcinogenesis through interaction interaction with the signaling pathway NOTCH1/MMP9. Moreover, antioxidant reduce the inflammatory process by inhibiting the synthesis of inflammatory mediators, and inhibit the mechanisms of cell proliferation by inducing apoptosis. In brief, nutraceuticals have gained a huge clinical interest since they could be used along with traditional therapy. Bioavailability studies of nutracetical supplements guarantee a correct intake of the substance by oral administration, a matter which would not have been posible to have entirely with the consumprtion of regular food only.
Lingua originaleEnglish
pagine (da-a)123-129
Numero di pagine7
RivistaEuroMediterranean Biomedical Journal
Volume11
Stato di pubblicazionePublished - 2016

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Fingerprint Entra nei temi di ricerca di 'INFLAMMATORY BOWEL DISEASE AND COLORECTAL CANCER, NUTRACEUTICAL ASPECTS'. Insieme formano una fingerprint unica.

  • Cita questo

    Tomasello, G., Carini, F., Leone, A., Rappa, F., Jurjus, R., Assi, T. B., Rappa, F., Geagea, A. G., Trovato, E., Tomasello, G., Assi, T. B., Assi, T. B., & Jurjus, A. (2016). INFLAMMATORY BOWEL DISEASE AND COLORECTAL CANCER, NUTRACEUTICAL ASPECTS. EuroMediterranean Biomedical Journal, 11, 123-129.