Incidence of venous thromboembolism in patients undergoing thoracotomy for lung cancer.

Sergio Siragusa, Massimo Cajozzo, Alessandra Malato, Alessandra Malato, Mark Crowther, Sergio Siragusa, Andrea Imperatori, Walter Ageno, James Douketis, Nicola Rotolo, Francesco Dentali

Risultato della ricerca: Articlepeer review

48 Citazioni (Scopus)


Limited information exists on the incidence of symptomatic venous thromboembolism (vTE) in patients undergoing chest surgery for lung cancer. Several factors increase the thromboembolic risk in patients undergoing surgery for lung cancer: the intrinsic procoagulant effect of cancer,extensive surgical intervention, dependent limb position in the operating room, and vessel injury consequent to the operation. Furthermore,these patients might be especially vulnerable to pulmonary embolism (PE) because of the loss of lung tissue and the presence of chronic obstructive pulmonary disease and cardiovascular diseases caused by smoking.tOlder studies found a very high incidence of thromboembolic events in these patients.2''3However, the risk of thromboembolic complications in lung cancer surgery might have changed over the last years. Extensive use of antithrombotic prophylaxis, improvement in surgical techniques and perioperative care, and more prompt mobilization might have reduced the risk of VTE.Therefore, the aim of our study was to provide up-to-date reliable data on the incidence of venous thromboembolic complication in a large cohort of patients undergoing chest surgery for malignant lung disease. Furthermore, the raw mortality rate and the mortalityrate related to PE were evaluated.
Lingua originaleEnglish
pagine (da-a)705-706
Numero di pagine2
RivistaJournal of Thoracic and Cardiovascular Surgery
Volume135 (3)
Stato di pubblicazionePublished - 2008

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.2700.2740???
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