INCIDENCE OF AMYOTROPHIC LATERAL SCLEROSIS IN SICILY: A POPULATION BASED STUDY.

Rossella Spataro; Marco D'Amelio; Vincenzo La Bella; Paolo Ragonese; Giovanni Savettieri; Paolo Aridon; Gianluigi Mancardi; Francesco Marrosu; Francesca Trojsi; Kalliopi Marinou; Cristina Moglia; Valeria Piras; Ilaria Bartolomei; Giuseppe Marangi; Stefania Cammarosano; Amelia Conte; Giuseppe Lauria Pinter; Marco Luigetti; Alan E. Renton; Irene Ossola; Serena Lattante; Yevgeniya Abramzon; Gianluca Floris; Claudia Ricci; Emanuela Costantino; William Sproviero; Leslie D. Parish; Simona Portaro; Lucia Ulgheri; Carla Pani; null Pharm.D.; Anna Laiola; null Antonio Canosa; Laura Papetti; Paolo Volanti; Carmelo Rodolico; Giuseppe Fuda; Francesco Izzo; Paola Cossu; Maura Brunetti; Patrizia Sola; Sara Gallo; Maria Rosaria Monsurrò; Andrea Calvo; Sara Gallo; Giuliana Solinas; Sara Gallo; Jessica Mandrioli; Elisa Majounie; Anna Ticca; Giuseppe Borghero; Paola Origone; Claudia Caponnetto; Maura Pugliatti; Stefania Battistini; Bryan J. Traynor; Mario Sabatelli; Maria Rita Murru; Giuliana Solinas; Francesca Luisa Conforti; Marcella Zollino; Gabriella Restagno; Antonino Cannas; Paola Mandich; Isabella Simone; Fabrizio Pisano; Giancarlo Logroscino; Silvana Penco; Andrea Calvo; Adriano Chiò; Maria Giovanna Marrosu; Massimo Corbo; Fabrizio Salvi; Gabriele Mora; Aldo Quattrone; Fabio Giannini; Gioacchino Tedeschi; Antonio Gambardella; Christian Lunetta; Maria Alessandra Sotgiu; Alfonsa Claudia Taiello

INCIDENCE OF AMYOTROPHIC LATERAL SCLEROSIS IN SICILY: A POPULATION BASED STUDY.

Rossella Spataro, Marco D'Amelio, Vincenzo La Bella, Paolo Ragonese, Giovanni Savettieri, Paolo Aridon, Gianluigi Mancardi, Francesco Marrosu, Francesca Trojsi, Kalliopi Marinou, Cristina Moglia, Valeria Piras, Ilaria Bartolomei, Giuseppe Marangi, Stefania Cammarosano, Amelia Conte, Giuseppe Lauria Pinter, Marco Luigetti, Alan E. Renton, Irene OssolaSerena Lattante, Yevgeniya Abramzon, Gianluca Floris, Claudia Ricci, Emanuela Costantino, William Sproviero, Leslie D. Parish, Simona Portaro, Lucia Ulgheri, Carla Pani, Pharm.D., Anna Laiola, Antonio Canosa, Laura Papetti, Paolo Volanti, Carmelo Rodolico, Giuseppe Fuda, Francesco Izzo, Paola Cossu, Maura Brunetti, Patrizia Sola, Sara Gallo, Maria Rosaria Monsurrò, Andrea Calvo, Sara Gallo, Giuliana Solinas, Sara Gallo, Jessica Mandrioli, Elisa Majounie, Anna Ticca, Giuseppe Borghero, Paola Origone, Claudia Caponnetto, Maura Pugliatti, Stefania Battistini, Bryan J. Traynor, Mario Sabatelli, Maria Rita Murru, Giuliana Solinas, Francesca Luisa Conforti, Marcella Zollino, Gabriella Restagno, Antonino Cannas, Paola Mandich, Isabella Simone, Fabrizio Pisano, Giancarlo Logroscino, Silvana Penco, Andrea Calvo, Adriano Chiò, Maria Giovanna Marrosu, Massimo Corbo, Fabrizio Salvi, Gabriele Mora, Aldo Quattrone, Fabio Giannini, Gioacchino Tedeschi, Antonio Gambardella, Christian Lunetta, Maria Alessandra Sotgiu, Alfonsa Claudia Taiello

Biomedicina, Neuroscienze e Diagnostica avanzata

Risultato della ricerca: Article › peer review

68 Citazioni (Scopus)

Abstract

Our objective was to investigate incidence of amyotrophic lateral sclerosis (ALS) in Sicily, southern Italy, by means of apopulation based study. We included people with ALS resident in fi ve Sicilian provinces, whose onset occurred in thetwo-year period 2005 2006 (population at 31 December 2006: 3,481,096 inhabitants). A multisource case-fi nding procedurewas adopted and patients were classifi ed as affected by ALS according to revised El Escorial criteria. During thetwo-year surveillance period, 97 patients meeting eligibility criteria included 57 males (58.8%) and 40 females (41.2%).Crude annual incidence rate was 1.4/100,000 person years (95% CI 1.33 1.47). The incidence rate was higher in males(1.71/100,000; CI 1.61 1.81) than in females (1.11/100,000; CI 1.01 1.21). Standardized incidence rate for the totalpopulation in the 45 74-years-old age group was 3.22 (CI 3.11 3.33). Prevalence rate was 6.0/100,000 (CI 5.97 6.03),higher in males (7.1/100,000; CI 7.02 7.18) than females (4.9/100,000; CI 4.86 4.94). In conclusion, ALS rates observedin the present study are higher in males than females, with a peak of incidence at 70 years of age in both genders. Thesefi ndings are consistent with those of other population based European studies

Lingua originale	English
pagine (da-a)	284-287
Numero di pagine	4
Rivista	Amyotrophic Lateral Sclerosis
Volume	13
Stato di pubblicazione	Published - 2012

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Spataro, R., D'Amelio, M., La Bella, V., Ragonese, P., Savettieri, G., Aridon, P., Mancardi, G., Marrosu, F., Trojsi, F., Marinou, K., Moglia, C., Piras, V., Bartolomei, I., Marangi, G., Cammarosano, S., Conte, A., Pinter, G. L., Luigetti, M., Renton, A. E., ... Taiello, A. C. (2012). INCIDENCE OF AMYOTROPHIC LATERAL SCLEROSIS IN SICILY: A POPULATION BASED STUDY. Amyotrophic Lateral Sclerosis, 13, 284-287.

Spataro, R , D'Amelio, M , La Bella, V , Ragonese, P , Savettieri, G , Aridon, P, Mancardi, G, Marrosu, F, Trojsi, F, Marinou, K, Moglia, C, Piras, V, Bartolomei, I, Marangi, G, Cammarosano, S, Conte, A, Pinter, GL, Luigetti, M, Renton, AE, Ossola, I, Lattante, S, Abramzon, Y, Floris, G, Ricci, C, Costantino, E, Sproviero, W, Parish, LD, Portaro, S, Ulgheri, L, Pani, C, Pharm.D., Laiola, A, Antonio Canosa, Papetti, L, Volanti, P, Rodolico, C, Fuda, G, Izzo, F, Cossu, P, Brunetti, M, Sola, P, Gallo, S, Monsurrò, MR, Calvo, A, Gallo, S, Solinas, G, Gallo, S, Mandrioli, J, Majounie, E, Ticca, A, Borghero, G, Origone, P, Caponnetto, C, Pugliatti, M, Battistini, S, Traynor, BJ, Sabatelli, M, Murru, MR, Solinas, G, Conforti, FL, Zollino, M, Restagno, G, Cannas, A, Mandich, P, Simone, I, Pisano, F, Logroscino, G, Penco, S, Calvo, A, Chiò, A, Marrosu, MG, Corbo, M, Salvi, F, Mora, G, Quattrone, A, Giannini, F, Tedeschi, G, Gambardella, A, Lunetta, C, Sotgiu, MA & Taiello, AC 2012, 'INCIDENCE OF AMYOTROPHIC LATERAL SCLEROSIS IN SICILY: A POPULATION BASED STUDY.', Amyotrophic Lateral Sclerosis, vol. 13, pagg. 284-287.

@article{bbbe51dc432c40a9abceeff270fd2468,

title = "INCIDENCE OF AMYOTROPHIC LATERAL SCLEROSIS IN SICILY: A POPULATION BASED STUDY.",

abstract = "Our objective was to investigate incidence of amyotrophic lateral sclerosis (ALS) in Sicily, southern Italy, by means of apopulation based study. We included people with ALS resident in fi ve Sicilian provinces, whose onset occurred in thetwo-year period 2005 2006 (population at 31 December 2006: 3,481,096 inhabitants). A multisource case-fi nding procedurewas adopted and patients were classifi ed as affected by ALS according to revised El Escorial criteria. During thetwo-year surveillance period, 97 patients meeting eligibility criteria included 57 males (58.8%) and 40 females (41.2%).Crude annual incidence rate was 1.4/100,000 person years (95% CI 1.33 1.47). The incidence rate was higher in males(1.71/100,000; CI 1.61 1.81) than in females (1.11/100,000; CI 1.01 1.21). Standardized incidence rate for the totalpopulation in the 45 74-years-old age group was 3.22 (CI 3.11 3.33). Prevalence rate was 6.0/100,000 (CI 5.97 6.03),higher in males (7.1/100,000; CI 7.02 7.18) than females (4.9/100,000; CI 4.86 4.94). In conclusion, ALS rates observedin the present study are higher in males than females, with a peak of incidence at 70 years of age in both genders. Thesefi ndings are consistent with those of other population based European studies",

keywords = "amyotrophic lateral sclerosis, epidemiology, incidence, population-based, sicily, amyotrophic lateral sclerosis, epidemiology, incidence, population-based, sicily",

author = "Rossella Spataro and Marco D'Amelio and {La Bella}, Vincenzo and Paolo Ragonese and Giovanni Savettieri and Paolo Aridon and Gianluigi Mancardi and Francesco Marrosu and Francesca Trojsi and Kalliopi Marinou and Cristina Moglia and Valeria Piras and Ilaria Bartolomei and Giuseppe Marangi and Stefania Cammarosano and Amelia Conte and Pinter, {Giuseppe Lauria} and Marco Luigetti and Renton, {Alan E.} and Irene Ossola and Serena Lattante and Yevgeniya Abramzon and Gianluca Floris and Claudia Ricci and Emanuela Costantino and William Sproviero and Parish, {Leslie D.} and Simona Portaro and Lucia Ulgheri and Carla Pani and Pharm.D. and Anna Laiola and {Antonio Canosa} and Laura Papetti and Paolo Volanti and Carmelo Rodolico and Giuseppe Fuda and Francesco Izzo and Paola Cossu and Maura Brunetti and Patrizia Sola and Sara Gallo and Monsurr{\`o}, {Maria Rosaria} and Andrea Calvo and Sara Gallo and Giuliana Solinas and Sara Gallo and Jessica Mandrioli and Elisa Majounie and Anna Ticca and Giuseppe Borghero and Paola Origone and Claudia Caponnetto and Maura Pugliatti and Stefania Battistini and Traynor, {Bryan J.} and Mario Sabatelli and Murru, {Maria Rita} and Giuliana Solinas and Conforti, {Francesca Luisa} and Marcella Zollino and Gabriella Restagno and Antonino Cannas and Paola Mandich and Isabella Simone and Fabrizio Pisano and Giancarlo Logroscino and Silvana Penco and Andrea Calvo and Adriano Chi{\`o} and Marrosu, {Maria Giovanna} and Massimo Corbo and Fabrizio Salvi and Gabriele Mora and Aldo Quattrone and Fabio Giannini and Gioacchino Tedeschi and Antonio Gambardella and Christian Lunetta and Sotgiu, {Maria Alessandra} and Taiello, {Alfonsa Claudia}",

year = "2012",

language = "English",

volume = "13",

pages = "284--287",

journal = "Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration",

issn = "2167-8421",

publisher = "Informa Healthcare",

}

TY - JOUR

T1 - INCIDENCE OF AMYOTROPHIC LATERAL SCLEROSIS IN SICILY: A POPULATION BASED STUDY.

AU - Spataro, Rossella

AU - D'Amelio, Marco

AU - La Bella, Vincenzo

AU - Ragonese, Paolo

AU - Savettieri, Giovanni

AU - Aridon, Paolo

AU - Mancardi, Gianluigi

AU - Marrosu, Francesco

AU - Trojsi, Francesca

AU - Marinou, Kalliopi

AU - Moglia, Cristina

AU - Piras, Valeria

AU - Bartolomei, Ilaria

AU - Marangi, Giuseppe

AU - Cammarosano, Stefania

AU - Conte, Amelia

AU - Pinter, Giuseppe Lauria

AU - Luigetti, Marco

AU - Renton, Alan E.

AU - Ossola, Irene

AU - Lattante, Serena

AU - Abramzon, Yevgeniya

AU - Floris, Gianluca

AU - Ricci, Claudia

AU - Costantino, Emanuela

AU - Sproviero, William

AU - Parish, Leslie D.

AU - Portaro, Simona

AU - Ulgheri, Lucia

AU - Pani, Carla

AU - Pharm.D., null

AU - Laiola, Anna

AU - Antonio Canosa, null

AU - Papetti, Laura

AU - Volanti, Paolo

AU - Rodolico, Carmelo

AU - Fuda, Giuseppe

AU - Izzo, Francesco

AU - Cossu, Paola

AU - Brunetti, Maura

AU - Sola, Patrizia

AU - Gallo, Sara

AU - Monsurrò, Maria Rosaria

AU - Calvo, Andrea

AU - Gallo, Sara

AU - Solinas, Giuliana

AU - Gallo, Sara

AU - Mandrioli, Jessica

AU - Majounie, Elisa

AU - Ticca, Anna

AU - Borghero, Giuseppe

AU - Origone, Paola

AU - Caponnetto, Claudia

AU - Pugliatti, Maura

AU - Battistini, Stefania

AU - Traynor, Bryan J.

AU - Sabatelli, Mario

AU - Murru, Maria Rita

AU - Solinas, Giuliana

AU - Conforti, Francesca Luisa

AU - Zollino, Marcella

AU - Restagno, Gabriella

AU - Cannas, Antonino

AU - Mandich, Paola

AU - Simone, Isabella

AU - Pisano, Fabrizio

AU - Logroscino, Giancarlo

AU - Penco, Silvana

AU - Calvo, Andrea

AU - Chiò, Adriano

AU - Marrosu, Maria Giovanna

AU - Corbo, Massimo

AU - Salvi, Fabrizio

AU - Mora, Gabriele

AU - Quattrone, Aldo

AU - Giannini, Fabio

AU - Tedeschi, Gioacchino

AU - Gambardella, Antonio

AU - Lunetta, Christian

AU - Sotgiu, Maria Alessandra

AU - Taiello, Alfonsa Claudia

PY - 2012

Y1 - 2012

N2 - Our objective was to investigate incidence of amyotrophic lateral sclerosis (ALS) in Sicily, southern Italy, by means of apopulation based study. We included people with ALS resident in fi ve Sicilian provinces, whose onset occurred in thetwo-year period 2005 2006 (population at 31 December 2006: 3,481,096 inhabitants). A multisource case-fi nding procedurewas adopted and patients were classifi ed as affected by ALS according to revised El Escorial criteria. During thetwo-year surveillance period, 97 patients meeting eligibility criteria included 57 males (58.8%) and 40 females (41.2%).Crude annual incidence rate was 1.4/100,000 person years (95% CI 1.33 1.47). The incidence rate was higher in males(1.71/100,000; CI 1.61 1.81) than in females (1.11/100,000; CI 1.01 1.21). Standardized incidence rate for the totalpopulation in the 45 74-years-old age group was 3.22 (CI 3.11 3.33). Prevalence rate was 6.0/100,000 (CI 5.97 6.03),higher in males (7.1/100,000; CI 7.02 7.18) than females (4.9/100,000; CI 4.86 4.94). In conclusion, ALS rates observedin the present study are higher in males than females, with a peak of incidence at 70 years of age in both genders. Thesefi ndings are consistent with those of other population based European studies

AB - Our objective was to investigate incidence of amyotrophic lateral sclerosis (ALS) in Sicily, southern Italy, by means of apopulation based study. We included people with ALS resident in fi ve Sicilian provinces, whose onset occurred in thetwo-year period 2005 2006 (population at 31 December 2006: 3,481,096 inhabitants). A multisource case-fi nding procedurewas adopted and patients were classifi ed as affected by ALS according to revised El Escorial criteria. During thetwo-year surveillance period, 97 patients meeting eligibility criteria included 57 males (58.8%) and 40 females (41.2%).Crude annual incidence rate was 1.4/100,000 person years (95% CI 1.33 1.47). The incidence rate was higher in males(1.71/100,000; CI 1.61 1.81) than in females (1.11/100,000; CI 1.01 1.21). Standardized incidence rate for the totalpopulation in the 45 74-years-old age group was 3.22 (CI 3.11 3.33). Prevalence rate was 6.0/100,000 (CI 5.97 6.03),higher in males (7.1/100,000; CI 7.02 7.18) than females (4.9/100,000; CI 4.86 4.94). In conclusion, ALS rates observedin the present study are higher in males than females, with a peak of incidence at 70 years of age in both genders. Thesefi ndings are consistent with those of other population based European studies

KW - amyotrophic lateral sclerosis

KW - epidemiology

KW - incidence

KW - population-based

KW - sicily

KW - amyotrophic lateral sclerosis

KW - epidemiology

KW - incidence

KW - population-based

KW - sicily

UR - http://hdl.handle.net/10447/64569

M3 - Article

SN - 2167-8421

VL - 13

SP - 284

EP - 287

JO - Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

JF - Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

ER -

INCIDENCE OF AMYOTROPHIC LATERAL SCLEROSIS IN SICILY: A POPULATION BASED STUDY.

Abstract

All Science Journal Classification (ASJC) codes

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