In vitro activities of tetracyclines against different clones of multidrug-resistant Acinetobacter baumannii isolates from two Iranian hospitals.

Caterina Mammina, Teresa Maria Assunta Fasciana, Celestino Bonura, Omid Pajand, Zoya Hojabri, Mohammad Reza Nahaei, Tahereh Pirzadeh, Farid Hajibonabi, Mohammad Aghazadeh

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4 Citazioni (Scopus)

Abstract

Acinetobacter baumannii has emerged as one of the most challenging healthcare-related pathogens and its occurrence has increased worldwide, especially in patients admitted to intensive care units. A. baumannii isolates are frequently resistant to multiple antimicrobial agents and there are recent reports of isolates resistant to virtually all clinically relevant drugs. In the present study, the in vitro activities of tigecycline, minocycline and doxycycline against 67 MDR-AB isolates recovered from 29 burn and 38 non-burn Iranian patients hospitalised in Tehran and Tabriz, respectively, were studied. Tigecycline and minocycline may be still considered effective therapeutic options for MDR-AB infections. However, ongoing monitoring of A. baumannii susceptibility to these antibiotics is required.
Lingua originaleEnglish
pagine (da-a)476-478
Numero di pagine3
RivistaInternational Journal of Antimicrobial Agents
Volume43
Stato di pubblicazionePublished - 2014

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All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases
  • Pharmacology (medical)

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