In situ delivery of corticosteroids for treatment of oral diseases

Risultato della ricerca: Articlepeer review

3 Citazioni (Scopus)

Abstract

In many mucocutaneous disorders, corticosteroids therapy is currently central. Systemic therapy is restricted to severe disorders whereas topical applications are considered as the first-line treatment. The oral cavity environment, the medication form and other factors related to the delivery method are key factors for the therapy efficiency and effectiveness. Current marketed medications are not able to avoid wrong drug exposure and scarce patients' compliance. Innovative in situ delivery systems are able to prolong the drug retention time on the mucosa and to avoid the drawbacks of conventional formulations. This review is intended to give a general overview of oral mucocutaneous pathologies and highlight the potential of new technologies in designing innovative delivery systems able to release corticosteroids in situ for the treatment of various oral cavity disorders.
Lingua originaleEnglish
pagine (da-a)899-914
Numero di pagine16
RivistaTherapeutic Delivery
Volume8
Stato di pubblicazionePublished - 2017

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

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