Impact of virus eradication in patients with compensated hepatitis C virus-related cirrhosis: competing risks and multistate model

Bruno, S.; Boccaccio, V.; Rossi, S.; Craxì, A.; Cammà, C.

Risultato della ricerca: Article

13 Citazioni (Scopus)

Abstract

No published study to date has provided a careful analysis of the effects of a sustained viral response(SVR) on the outcomes of patients with compensated hepatitis C virus(HCV)-related cirrhosis in relation to the degree of portal hypertension. Therefore, we estimated the impact of achieving SVR on disease progression, hepatocellular carcinoma(HCC) development and mortality in a large cohort of HCV patients with cirrhosis with or without oesophageal varices(OVs) at the start of antiviral therapy.
Lingua originaleEnglish
pagine (da-a)-
Numero di pagine25
RivistaLiver International
Stato di pubblicazionePublished - 2016

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Hepacivirus
Fibrosis
Viruses
Esophageal and Gastric Varices
Portal Hypertension
Antiviral Agents
Disease Progression
Hepatocellular Carcinoma
Mortality
Therapeutics

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Impact of virus eradication in patients with compensated hepatitis C virus-related cirrhosis: competing risks and multistate model. / Bruno, S.; Boccaccio, V.; Rossi, S.; Craxì, A.; Cammà, C.

In: Liver International, 2016, pag. -.

Risultato della ricerca: Article

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abstract = "No published study to date has provided a careful analysis of the effects of a sustained viral response(SVR) on the outcomes of patients with compensated hepatitis C virus(HCV)-related cirrhosis in relation to the degree of portal hypertension. Therefore, we estimated the impact of achieving SVR on disease progression, hepatocellular carcinoma(HCC) development and mortality in a large cohort of HCV patients with cirrhosis with or without oesophageal varices(OVs) at the start of antiviral therapy.",
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AU - Bruno, S.; Boccaccio, V.; Rossi, S.; Craxì, A.; Cammà, C.

AU - Craxi, Antonio

AU - Di Marco, Vito

AU - Camma', Calogero

AU - Petta, Salvatore

AU - Calvaruso, Vincenza

AU - Enea, Marco

PY - 2016

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N2 - No published study to date has provided a careful analysis of the effects of a sustained viral response(SVR) on the outcomes of patients with compensated hepatitis C virus(HCV)-related cirrhosis in relation to the degree of portal hypertension. Therefore, we estimated the impact of achieving SVR on disease progression, hepatocellular carcinoma(HCC) development and mortality in a large cohort of HCV patients with cirrhosis with or without oesophageal varices(OVs) at the start of antiviral therapy.

AB - No published study to date has provided a careful analysis of the effects of a sustained viral response(SVR) on the outcomes of patients with compensated hepatitis C virus(HCV)-related cirrhosis in relation to the degree of portal hypertension. Therefore, we estimated the impact of achieving SVR on disease progression, hepatocellular carcinoma(HCC) development and mortality in a large cohort of HCV patients with cirrhosis with or without oesophageal varices(OVs) at the start of antiviral therapy.

KW - HCV; SVR; Cirrhosis; multistate

UR - http://hdl.handle.net/10447/191006

M3 - Article

SP - -

JO - Liver International

JF - Liver International

SN - 1478-3223

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