Immunological and immunogenetic markers in sporadic Alzheimer's disease

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Abstract

Background: Common polymorphisms of genes controlling inflammation-modulating cytokines and acute-phase proteins which play important roles in the pathogenesis of Alzheimer''s disease (AD) have been shown to be associated with AD. Aims: The immunological and immunogenetic markers potentially useful for the AD risk evaluation and diagnosis are briefly reviewed. Conclusion: The state-of-the-art of immunological and immunogenetic markers of AD indicates that new tools and strategies are necessary to identify gene products useful as diagnostic tools.
Lingua originaleEnglish
pagine (da-a)163-166
Numero di pagine4
RivistaAging clinical and experimental research
Volume18
Stato di pubblicazionePublished - 2006

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Immunogenetics
Alzheimer Disease
Acute-Phase Proteins
Genes
Cytokines
Inflammation

All Science Journal Classification (ASJC) codes

  • Ageing
  • Geriatrics and Gerontology

Cita questo

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title = "Immunological and immunogenetic markers in sporadic Alzheimer's disease",
abstract = "Background: Common polymorphisms of genes controlling inflammation-modulating cytokines and acute-phase proteins which play important roles in the pathogenesis of Alzheimer''s disease (AD) have been shown to be associated with AD. Aims: The immunological and immunogenetic markers potentially useful for the AD risk evaluation and diagnosis are briefly reviewed. Conclusion: The state-of-the-art of immunological and immunogenetic markers of AD indicates that new tools and strategies are necessary to identify gene products useful as diagnostic tools.",
keywords = "Alzheimer’s disease, cytokines, immunogenetics, inflammation, proteomics",
author = "Calogero Caruso and {Colonna Romano}, Giuseppina and Giuseppina Candore and Domenico Lio and Letizia Scola",
year = "2006",
language = "English",
volume = "18",
pages = "163--166",
journal = "Aging clinical and experimental research",
issn = "1594-0667",
publisher = "Springer Verlag",

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TY - JOUR

T1 - Immunological and immunogenetic markers in sporadic Alzheimer's disease

AU - Caruso, Calogero

AU - Colonna Romano, Giuseppina

AU - Candore, Giuseppina

AU - Lio, Domenico

AU - Scola, Letizia

PY - 2006

Y1 - 2006

N2 - Background: Common polymorphisms of genes controlling inflammation-modulating cytokines and acute-phase proteins which play important roles in the pathogenesis of Alzheimer''s disease (AD) have been shown to be associated with AD. Aims: The immunological and immunogenetic markers potentially useful for the AD risk evaluation and diagnosis are briefly reviewed. Conclusion: The state-of-the-art of immunological and immunogenetic markers of AD indicates that new tools and strategies are necessary to identify gene products useful as diagnostic tools.

AB - Background: Common polymorphisms of genes controlling inflammation-modulating cytokines and acute-phase proteins which play important roles in the pathogenesis of Alzheimer''s disease (AD) have been shown to be associated with AD. Aims: The immunological and immunogenetic markers potentially useful for the AD risk evaluation and diagnosis are briefly reviewed. Conclusion: The state-of-the-art of immunological and immunogenetic markers of AD indicates that new tools and strategies are necessary to identify gene products useful as diagnostic tools.

KW - Alzheimer’s disease, cytokines, immunogenetics, inflammation, proteomics

UR - http://hdl.handle.net/10447/17627

M3 - Article

VL - 18

SP - 163

EP - 166

JO - Aging clinical and experimental research

JF - Aging clinical and experimental research

SN - 1594-0667

ER -