Il trattamento dei tumori stromali gastrici (GIST). Revisione della letteratura e descrizione di un caso

Massimo Cajozzo, Giuseppe Modica, Carmelo Sciume', Girolamo Geraci, Francesco Li Volsi, Calogero Cavaleri, Franco Pisello, Massimo Cajozzo, Carmelo Sciume, Giuseppe Modica, Girolamo Geraci, Calogero Cavaleri, Franco Pisello

Risultato della ricerca: Articlepeer review

Abstract

background: Gastrointestinal stromal tumors (GIST) are rare mesenchimal tumors that are characterized by constitutive overexpression of the tyrosin-kinase receptor KIT (CD 117). The authors analyse the basis of the treatment of gastric GIS, starting form the study of a recent observed case. Experimental design: Report of one case treated with endoscopic resection. Evaluation of treatment and 2-years follow- results: The treatment of gastric GIS I must be modulated on prognostic, genetic and molecular factors. These factors are the basis of the formation and growth of GIST. conclusions: Complete surgical extirpation without rupture remains the only curative treatment of localized favourable prognosis. Endoscopic treatment, as in our case, reflect the modulation of therapy on prognostic factors. Selective targeted therapy of metastatic disease yields encouraging clinical responses. Copyright © 2005 Edizioni Luigi Pozzi.
Lingua originaleItalian
pagine (da-a)377-381
Numero di pagine5
RivistaANNALI ITALIANI DI CHIRURGIA
Volume76
Stato di pubblicazionePublished - 2005

All Science Journal Classification (ASJC) codes

  • ???subjectarea.asjc.2700.2746???

Cita questo