MAIT cells are expanded in salivary glands of patients with Sjogren's syndrome and are IL-17 polarized. IL-7 and IL-23 induce IL-17 production activating two different pathways: IL-7 stimulation induces in fact a significant STAT3 and HIF1alpha upregulation, conversely, IL-23 stimulation significantly induces RORc overexpression in MAIT cells of patients with Sjogren's syndrome.
Lingua originaleEnglish
pagine (da-a)2002-2003
Numero di pagine2
RivistaEuropean Journal of Immunology
Stato di pubblicazionePublished - 2017

All Science Journal Classification (ASJC) codes

  • ???subjectarea.asjc.2700.2723???
  • ???subjectarea.asjc.2400.2403???


Entra nei temi di ricerca di 'IL-17 polarization of MAIT cells is derived from the activation of two different pathways'. Insieme formano una fingerprint unica.

Cita questo