Abstract
MAIT cells are expanded in salivary glands of patients with Sjogren's syndrome and are IL-17 polarized. IL-7 and IL-23 induce IL-17 production activating two different pathways: IL-7 stimulation induces in fact a significant STAT3 and HIF1alpha upregulation, conversely, IL-23 stimulation significantly induces RORc overexpression in MAIT cells of patients with Sjogren's syndrome.
Lingua originale | English |
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pagine (da-a) | 2002-2003 |
Numero di pagine | 2 |
Rivista | European Journal of Immunology |
Volume | 47 |
Stato di pubblicazione | Published - 2017 |
All Science Journal Classification (ASJC) codes
- Immunology and Allergy
- Immunology