Abstract
The complexity of biology literally calls for quantitative tools in order to support and validate biologists intuition and traditional qualitative descriptions. In this paper, the Replicator-Mutator models for Evolutionary Dynamics are validated/invalidated in a worst-case deterministic setting. These models analyze the DNA and RNA evolution or describe the population dynamics of viruses and bacteria. We identify the Fitness and the Replication Probability parameters of a genetic sequences, subject to a set of stringent constraints to have physical meaning and to guarantee positiveness. The conditional central estimate is determined in order to validate/invalidate the model. The effectiveness of the proposed procedure has been illustrated by means of simulation experiments while tests on real data are under concern.
| Lingua originale | English |
|---|---|
| Pagine | 1-6 |
| Numero di pagine | 6 |
| Stato di pubblicazione | Published - 2006 |
All Science Journal Classification (ASJC) codes
- Computer Science Applications
- Control and Systems Engineering
- Electrical and Electronic Engineering