Abstract
The complexity of biology literally calls for quantitative tools in order to support and validate biologists intuition and traditional qualitative descriptions. In this paper, the Replicator-Mutator models for Evolutionary Dynamics are validated/invalidated in a worst-case deterministic setting. These models analyze the DNA and RNA evolution or describe the population dynamics of viruses and bacteria. We identify the Fitness and the Replication Probability parameters of a genetic sequences, subject to a set of stringent constraints to have physical meaning and to guarantee positiveness. The conditional central estimate is determined in order to validate/invalidate the model. The effectiveness of the proposed procedure has been illustrated by means of simulation experiments while tests on real data are under concern.
Lingua originale | English |
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Pagine | 1-6 |
Numero di pagine | 6 |
Stato di pubblicazione | Published - 2006 |
All Science Journal Classification (ASJC) codes
- ???subjectarea.asjc.1700.1706???
- ???subjectarea.asjc.2200.2207???
- ???subjectarea.asjc.2200.2208???