Identification and validation of quasispecies models for biological systems

Laura Giarre, Paola Falugi

    Risultato della ricerca: Articlepeer review

    2 Citazioni (Scopus)


    An identification procedure for biological systems cast as quasi-species models is proposed. Their identification is a challenging problem because of the bilinear dependence on the parametersand their physical constraints. The proposed solution is within the framework of set-membership identification.%The bilinear dependence on parameters of the model and their physical constraints make the present issue challenging. We determine an estimate of the model parameters together with their interval of variability (Uncertainty Intervals), taking into account all the physical constraints. Invalidation/validation is performed on the basis of the predictive capability of the estimated models.The effectiveness of the proposed procedure has been illustrated by means of simulation experiments.
    Lingua originaleEnglish
    pagine (da-a)529-539
    Numero di pagine11
    Stato di pubblicazionePublished - 2009

    All Science Journal Classification (ASJC) codes

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    • ???subjectarea.asjc.1700.1700???
    • ???subjectarea.asjc.2200.2210???
    • ???subjectarea.asjc.2200.2208???


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