Identification and optimization of small molecule antagonists of vasoactive intestinal peptide receptor-1 (VIPR1)

Neelam Srivastava, Arvind Mathur, Lauren E. Kayser, Tajudheen Karatt, Kumaragurubaran K, Amrita Roy, Christopher B. Cooper, Jing Chen, Sukhen Karmakar, Anuradha Gupta, Yan Kong, Lalgudi S. Harikrishnan, David S. Nirschl, Maryellen Cvijic, George L. Trainor, Michael A. Poss, Neil T. Burford, Neelam Srivastava, Tai W. Wong

    Risultato della ricerca: Article

    7 Citazioni (Scopus)

    Abstract

    Identification, synthesis and structure-activity relationship of small-molecule VIPR1 antagonists encompassing two chemical series are described.
    Lingua originaleEnglish
    pagine (da-a)2287-2290
    Numero di pagine4
    RivistaBIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    Volume22
    Stato di pubblicazionePublished - 2012

      Fingerprint

    All Science Journal Classification (ASJC) codes

    • Biochemistry
    • Molecular Medicine
    • Molecular Biology
    • Pharmaceutical Science
    • Drug Discovery
    • Clinical Biochemistry
    • Organic Chemistry

    Cita questo

    Srivastava, N., Mathur, A., Kayser, L. E., Karatt, T., K, K., Roy, A., Cooper, C. B., Chen, J., Karmakar, S., Gupta, A., Kong, Y., Harikrishnan, L. S., Nirschl, D. S., Cvijic, M., Trainor, G. L., Poss, M. A., Burford, N. T., Srivastava, N., & Wong, T. W. (2012). Identification and optimization of small molecule antagonists of vasoactive intestinal peptide receptor-1 (VIPR1). BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 22, 2287-2290.