Identification and optimization of small molecule antagonists of vasoactive intestinal peptide receptor-1 (VIPR1)

Neelam Srivastava, Lalgudi S. Harikrishnan, David S. Nirschl, Maryellen Cvijic, George L. Trainor, Michael A. Poss, Neil T. Burford, Neelam Srivastava, Arvind Mathur, Lauren E. Kayser, Tajudheen Karatt, Kumaragurubaran K, Amrita Roy, Christopher B. Cooper, Jing Chen, Sukhen Karmakar, Anuradha Gupta, Tai W. Wong, Yan Kong

    Risultato della ricerca: Article

    6 Citazioni (Scopus)

    Abstract

    Identification, synthesis and structure-activity relationship of small-molecule VIPR1 antagonists encompassing two chemical series are described.
    Lingua originaleEnglish
    pagine (da-a)2287-2290
    Numero di pagine4
    RivistaBIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    Volume22
    Stato di pubblicazionePublished - 2012

    Fingerprint

    Receptors, Vasoactive Intestinal Polypeptide, Type I
    Molecules

    All Science Journal Classification (ASJC) codes

    • Biochemistry
    • Organic Chemistry
    • Clinical Biochemistry
    • Drug Discovery
    • Pharmaceutical Science
    • Molecular Biology
    • Molecular Medicine

    Cita questo

    Srivastava, N., Harikrishnan, L. S., Nirschl, D. S., Cvijic, M., Trainor, G. L., Poss, M. A., ... Kong, Y. (2012). Identification and optimization of small molecule antagonists of vasoactive intestinal peptide receptor-1 (VIPR1). BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 22, 2287-2290.

    Identification and optimization of small molecule antagonists of vasoactive intestinal peptide receptor-1 (VIPR1). / Srivastava, Neelam; Harikrishnan, Lalgudi S.; Nirschl, David S.; Cvijic, Maryellen; Trainor, George L.; Poss, Michael A.; Burford, Neil T.; Srivastava, Neelam; Mathur, Arvind; Kayser, Lauren E.; Karatt, Tajudheen; K, Kumaragurubaran; Roy, Amrita; Cooper, Christopher B.; Chen, Jing; Karmakar, Sukhen; Gupta, Anuradha; Wong, Tai W.; Kong, Yan.

    In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Vol. 22, 2012, pag. 2287-2290.

    Risultato della ricerca: Article

    Srivastava, N, Harikrishnan, LS, Nirschl, DS, Cvijic, M, Trainor, GL, Poss, MA, Burford, NT, Srivastava, N, Mathur, A, Kayser, LE, Karatt, T, K, K, Roy, A, Cooper, CB, Chen, J, Karmakar, S, Gupta, A, Wong, TW & Kong, Y 2012, 'Identification and optimization of small molecule antagonists of vasoactive intestinal peptide receptor-1 (VIPR1)', BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, pagg. 2287-2290.
    Srivastava, Neelam ; Harikrishnan, Lalgudi S. ; Nirschl, David S. ; Cvijic, Maryellen ; Trainor, George L. ; Poss, Michael A. ; Burford, Neil T. ; Srivastava, Neelam ; Mathur, Arvind ; Kayser, Lauren E. ; Karatt, Tajudheen ; K, Kumaragurubaran ; Roy, Amrita ; Cooper, Christopher B. ; Chen, Jing ; Karmakar, Sukhen ; Gupta, Anuradha ; Wong, Tai W. ; Kong, Yan. / Identification and optimization of small molecule antagonists of vasoactive intestinal peptide receptor-1 (VIPR1). In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2012 ; Vol. 22. pagg. 2287-2290.
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    abstract = "Identification, synthesis and structure-activity relationship of small-molecule VIPR1 antagonists encompassing two chemical series are described.",
    author = "Neelam Srivastava and Harikrishnan, {Lalgudi S.} and Nirschl, {David S.} and Maryellen Cvijic and Trainor, {George L.} and Poss, {Michael A.} and Burford, {Neil T.} and Neelam Srivastava and Arvind Mathur and Kayser, {Lauren E.} and Tajudheen Karatt and Kumaragurubaran K and Amrita Roy and Cooper, {Christopher B.} and Jing Chen and Sukhen Karmakar and Anuradha Gupta and Wong, {Tai W.} and Yan Kong",
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    AU - Srivastava, Neelam

    AU - Harikrishnan, Lalgudi S.

    AU - Nirschl, David S.

    AU - Cvijic, Maryellen

    AU - Trainor, George L.

    AU - Poss, Michael A.

    AU - Burford, Neil T.

    AU - Srivastava, Neelam

    AU - Mathur, Arvind

    AU - Kayser, Lauren E.

    AU - Karatt, Tajudheen

    AU - K, Kumaragurubaran

    AU - Roy, Amrita

    AU - Cooper, Christopher B.

    AU - Chen, Jing

    AU - Karmakar, Sukhen

    AU - Gupta, Anuradha

    AU - Wong, Tai W.

    AU - Kong, Yan

    PY - 2012

    Y1 - 2012

    N2 - Identification, synthesis and structure-activity relationship of small-molecule VIPR1 antagonists encompassing two chemical series are described.

    AB - Identification, synthesis and structure-activity relationship of small-molecule VIPR1 antagonists encompassing two chemical series are described.

    UR - http://hdl.handle.net/10447/105375

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    SP - 2287

    EP - 2290

    JO - Bioorganic and Medicinal Chemistry Letters

    JF - Bioorganic and Medicinal Chemistry Letters

    SN - 0960-894X

    ER -