Human Papillomavirus Infection: A Risk Factor for Oral and Oropharyngeal Cancers

Risultato della ricerca: Chapter

Abstract

A wide range of human papillomavirus (HPV) prevalence datais now available for head and neck squamous cell carcinomas(HNSCCs), especially for those cancers originating from theepithelial lining of the upper aero-digestive tract (UADT) (i.e.,the pharynx, the larynx, and the oral cavity). There is strongevidence that supports HPV as an etiological cause of headand neck carcinogenesis particularly for distinct oropharyngealsubsites. A specific molecular, histopathological, clinical,and prognostic profile is intimately connected with HPVinfection. While the role of HPV in oropharyngeal carcinogenesisis firmly acknowledged, its role in oral cancer is currentlybeing debated. Several recent studies suggest the importanceof correctly distinguishing HNSCCs by subsites, andutilizing more sensitive HPV-DNA detection techniques, indesigning future studies. Defining the HPV status of thetumor aids in the correct management of patients with oropharyngealcancers.
Lingua originaleEnglish
Titolo della pubblicazione ospiteTextbook of Oral Cancer. Prevention, Diagnosis and Management
Pagine31-45
Numero di pagine15
Stato di pubblicazionePublished - 2020

Fingerprint Entra nei temi di ricerca di 'Human Papillomavirus Infection: A Risk Factor for Oral and Oropharyngeal Cancers'. Insieme formano una fingerprint unica.

  • Cita questo

    Campisi, G., & Panzarella, V. (2020). Human Papillomavirus Infection: A Risk Factor for Oral and Oropharyngeal Cancers. In Textbook of Oral Cancer. Prevention, Diagnosis and Management (pagg. 31-45)