TY - JOUR
T1 - HIDRAdisk: validation of an innovative visual tool to assess the burden of hidradenitis suppurativa
AU - Pistone, Giuseppe
AU - Franchi, null
AU - Malara, null
AU - Amerio, null
AU - Deboli, Tommaso
AU - Prignano, null
AU - Dini, Valentina
AU - Casari, Alice
AU - Bertoldi, null
AU - Bettoli, null
AU - Stingeni, Luca
AU - Gualberti, null
AU - Saragaglia, null
AU - Potenza, Concetta
AU - Guanziroli, null
AU - Bianchi, Luca
AU - Fusano, null
AU - Musumeci, Maria Letizia
AU - Mancini, null
AU - Bianchi, null
AU - Patrizi, null
AU - Guarneri, Claudio
AU - Ardigò, null
AU - Fabbrocini, null
AU - Lo Schiavo, null
AU - Cusano, Francesco
AU - Pistone, Giuseppe
AU - Offidani, null
AU - Amerio, null
AU - Peris, Ketty
AU - Rongioletti, null
AU - Patrizi, Annalisa
AU - Parodi, Aurora
AU - Mancini, null
PY - 2019
Y1 - 2019
N2 - Background Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin disease characterized by painfulinflamed nodules, recurrent abscesses and fistulas located in apocrine gland–bearing body sites. The negative impact ofHS on patient’s quality of life (QoL) has been reported to be greater than other dermatologic conditions as psoriasis andatopic eczema, and its improvement is an important goal in disease management. Nowadays, there are no specific validated QoL instruments available for HS and generic dermatologic questionnaires are used.Objective The objective of this study was to demonstrate the validity, reliability and responsiveness of HIDRAdisk, anew innovative tool designed for rapid assessment of HS burden and, at the same time, an intuitive graphic visualizationof the measurement outcome.Methods A multicentre, longitudinal, observational study was conducted to validate the HIDRAdisk compared withother validated questionnaires [Skindex-16, Dermatology Life Quality Index (DLQI), Work Productivity and Activity Impairment–General Health (WPAI:GH)] and to evaluate its correlation with disease severity in Italian patients with anydegree of HS severity, as measured by Hurley stage and HS Physician Global Assessment (HS-PGA).Results A total of 140 patients (59% women; mean age 34.9 11.0 years) were enrolled in 27 dermatologic centres.HIDRAdisk showed a strong correlation with Skindex-16 and DLQI, and a good one with WPAI:GH (correlation coefficient: 0.7568, 0.6651 and 0.5947, respectively) and a statistically significant correlation with both Hurley stage and HSPGA. Very good internal consistency (Cronbach coefficient >0.80; intraclass correlation coefficient >0.6), with correlationbetween the 10 items, good test–retest reliability (Spearman correlation coefficient, 0.8331; P < 0.0001) and responsiveness to changes were demonstrated.Conclusion Our study shows that HIDRAdisk, a short and innovative visual HS QoL instrument, has been psychometrically validated in Italian language and it may help improve the management of HS once implemented in routine clinicalpractice
AB - Background Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin disease characterized by painfulinflamed nodules, recurrent abscesses and fistulas located in apocrine gland–bearing body sites. The negative impact ofHS on patient’s quality of life (QoL) has been reported to be greater than other dermatologic conditions as psoriasis andatopic eczema, and its improvement is an important goal in disease management. Nowadays, there are no specific validated QoL instruments available for HS and generic dermatologic questionnaires are used.Objective The objective of this study was to demonstrate the validity, reliability and responsiveness of HIDRAdisk, anew innovative tool designed for rapid assessment of HS burden and, at the same time, an intuitive graphic visualizationof the measurement outcome.Methods A multicentre, longitudinal, observational study was conducted to validate the HIDRAdisk compared withother validated questionnaires [Skindex-16, Dermatology Life Quality Index (DLQI), Work Productivity and Activity Impairment–General Health (WPAI:GH)] and to evaluate its correlation with disease severity in Italian patients with anydegree of HS severity, as measured by Hurley stage and HS Physician Global Assessment (HS-PGA).Results A total of 140 patients (59% women; mean age 34.9 11.0 years) were enrolled in 27 dermatologic centres.HIDRAdisk showed a strong correlation with Skindex-16 and DLQI, and a good one with WPAI:GH (correlation coefficient: 0.7568, 0.6651 and 0.5947, respectively) and a statistically significant correlation with both Hurley stage and HSPGA. Very good internal consistency (Cronbach coefficient >0.80; intraclass correlation coefficient >0.6), with correlationbetween the 10 items, good test–retest reliability (Spearman correlation coefficient, 0.8331; P < 0.0001) and responsiveness to changes were demonstrated.Conclusion Our study shows that HIDRAdisk, a short and innovative visual HS QoL instrument, has been psychometrically validated in Italian language and it may help improve the management of HS once implemented in routine clinicalpractice
UR - http://hdl.handle.net/10447/345034
M3 - Article
SN - 0926-9959
VL - 33
SP - 766
EP - 773
JO - Journal of the European Academy of Dermatology and Venereology
JF - Journal of the European Academy of Dermatology and Venereology
ER -