Hepatic focal nodular hyperplasia: contrast-enhanced ultrasound findings with emphasis on lesion size, depth and liver echogenicity.

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    Abstract

    OBJECTIVE: To correlate contrast-enhanced ultrasound (CEUS) findings of hepatic focal nodular hyperplasia (FNH) with lesion size, depth and liver echogenicity and to compare CEUS with baseline US. METHODS: Two radiologists evaluated baseline US and CEUS examinations of 92 FNHs (mean size: 3.1 +/- 1.7 cm) in 71 patients (59 women and 12 men) to detect the "spoke-wheel" sign, central scar and feeding vessel. The FNHs were grouped and analysed by dimension, depth and liver echogenicity. RESULTS: At least one sign could be detected at CEUS in 27 out of 36 (75%) FNHs larger than 3 cm and in 17 out of 56 (30%) FNH measuring 3 cm or less (p < 0.0001). No statistically significant differences were noted between lesion depth or liver echogenicity and detection rate of these signs at CEUS (p > 0.05) as well as between CEUS or baseline US/CD with regard to lesion size, depth or liver echogenicity (p > 0.05). CONCLUSION: The detection rate of the central scar and spoke-wheel sign in FNH at CEUS is strongly dependent on lesion size and CEUS can confidently diagnose most FNHs larger than 3 cm.
    Lingua originaleEnglish
    pagine (da-a)2248-2256
    Numero di pagine9
    RivistaEuropean Radiology
    Volume20
    Stato di pubblicazionePublished - 2010

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    Focal Nodular Hyperplasia
    Liver
    Cicatrix

    All Science Journal Classification (ASJC) codes

    • Radiology Nuclear Medicine and imaging

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    @article{c8b547b915f94ddf8f753e233ace43ff,
    title = "Hepatic focal nodular hyperplasia: contrast-enhanced ultrasound findings with emphasis on lesion size, depth and liver echogenicity.",
    abstract = "OBJECTIVE: To correlate contrast-enhanced ultrasound (CEUS) findings of hepatic focal nodular hyperplasia (FNH) with lesion size, depth and liver echogenicity and to compare CEUS with baseline US. METHODS: Two radiologists evaluated baseline US and CEUS examinations of 92 FNHs (mean size: 3.1 +/- 1.7 cm) in 71 patients (59 women and 12 men) to detect the {"}spoke-wheel{"} sign, central scar and feeding vessel. The FNHs were grouped and analysed by dimension, depth and liver echogenicity. RESULTS: At least one sign could be detected at CEUS in 27 out of 36 (75{\%}) FNHs larger than 3 cm and in 17 out of 56 (30{\%}) FNH measuring 3 cm or less (p < 0.0001). No statistically significant differences were noted between lesion depth or liver echogenicity and detection rate of these signs at CEUS (p > 0.05) as well as between CEUS or baseline US/CD with regard to lesion size, depth or liver echogenicity (p > 0.05). CONCLUSION: The detection rate of the central scar and spoke-wheel sign in FNH at CEUS is strongly dependent on lesion size and CEUS can confidently diagnose most FNHs larger than 3 cm.",
    keywords = "Focal nodular hyperplasia, Ultrasonography, Contrast media, Microbubbles, Liver diseases",
    author = "Massimo Midiri and Roberto Lagalla and Bartolotta, {Tommaso Vincenzo} and Domenica Matranga and Adele Taibbi and Bartolotta, {Tommaso Vincenzo}",
    year = "2010",
    language = "English",
    volume = "20",
    pages = "2248--2256",
    journal = "European Radiology",
    issn = "0938-7994",
    publisher = "Springer Verlag",

    }

    TY - JOUR

    T1 - Hepatic focal nodular hyperplasia: contrast-enhanced ultrasound findings with emphasis on lesion size, depth and liver echogenicity.

    AU - Midiri, Massimo

    AU - Lagalla, Roberto

    AU - Bartolotta, Tommaso Vincenzo

    AU - Matranga, Domenica

    AU - Taibbi, Adele

    AU - Bartolotta, Tommaso Vincenzo

    PY - 2010

    Y1 - 2010

    N2 - OBJECTIVE: To correlate contrast-enhanced ultrasound (CEUS) findings of hepatic focal nodular hyperplasia (FNH) with lesion size, depth and liver echogenicity and to compare CEUS with baseline US. METHODS: Two radiologists evaluated baseline US and CEUS examinations of 92 FNHs (mean size: 3.1 +/- 1.7 cm) in 71 patients (59 women and 12 men) to detect the "spoke-wheel" sign, central scar and feeding vessel. The FNHs were grouped and analysed by dimension, depth and liver echogenicity. RESULTS: At least one sign could be detected at CEUS in 27 out of 36 (75%) FNHs larger than 3 cm and in 17 out of 56 (30%) FNH measuring 3 cm or less (p < 0.0001). No statistically significant differences were noted between lesion depth or liver echogenicity and detection rate of these signs at CEUS (p > 0.05) as well as between CEUS or baseline US/CD with regard to lesion size, depth or liver echogenicity (p > 0.05). CONCLUSION: The detection rate of the central scar and spoke-wheel sign in FNH at CEUS is strongly dependent on lesion size and CEUS can confidently diagnose most FNHs larger than 3 cm.

    AB - OBJECTIVE: To correlate contrast-enhanced ultrasound (CEUS) findings of hepatic focal nodular hyperplasia (FNH) with lesion size, depth and liver echogenicity and to compare CEUS with baseline US. METHODS: Two radiologists evaluated baseline US and CEUS examinations of 92 FNHs (mean size: 3.1 +/- 1.7 cm) in 71 patients (59 women and 12 men) to detect the "spoke-wheel" sign, central scar and feeding vessel. The FNHs were grouped and analysed by dimension, depth and liver echogenicity. RESULTS: At least one sign could be detected at CEUS in 27 out of 36 (75%) FNHs larger than 3 cm and in 17 out of 56 (30%) FNH measuring 3 cm or less (p < 0.0001). No statistically significant differences were noted between lesion depth or liver echogenicity and detection rate of these signs at CEUS (p > 0.05) as well as between CEUS or baseline US/CD with regard to lesion size, depth or liver echogenicity (p > 0.05). CONCLUSION: The detection rate of the central scar and spoke-wheel sign in FNH at CEUS is strongly dependent on lesion size and CEUS can confidently diagnose most FNHs larger than 3 cm.

    KW - Focal nodular hyperplasia, Ultrasonography, Contrast media, Microbubbles, Liver diseases

    UR - http://hdl.handle.net/10447/61236

    M3 - Article

    VL - 20

    SP - 2248

    EP - 2256

    JO - European Radiology

    JF - European Radiology

    SN - 0938-7994

    ER -