HELICOBACTER PYLORI AND BARRETT'S ESOPHAGUS: A PROTECTIVE FACTOR OR REAL CAUSE?

Giovanni Tomasello, Angelo Leone, Francesco Carini, Rosalyn Jurjus, Margherita Mazzola, Tomasello, Jurjus

Risultato della ricerca: Article

4 Citazioni (Scopus)

Abstract

Nothwithstanding the definite aethiopathogenetic path of certain diseases, the relationship between Helicobacter Pylori (H. Pylori) and barrett's esophagus (BE), a condition that increases the risk for dysplasia and consequently adenocarcinoma of the distal esophagus and esophagogastric junction, remains uncertain. this paper reviews the current scientific literature with emphasis on the protective correlation between H. Pylori infection and BE, and demonstrates that a causal relathionship has not been disproved with certainty. Furthermore, H. Pylori infection could pose a risk for the onset of gastroesophageal reflux disease (GERD), which could in turn trigger BE, a precancerous lesion and subsequently cause cancer. by analyzing the current available data, this article tries to verify that H. Pylori infection is the underlying cause of esophageal cancer.
Lingua originaleEnglish
pagine (da-a)9-15
Numero di pagine7
RivistaJOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS
Volume31
Stato di pubblicazionePublished - 2017

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Immunology and Allergy
  • Physiology
  • Immunology
  • Oncology
  • Endocrinology
  • Physiology (medical)
  • Cancer Research

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