Habitual fish intake and clinically silent carotid atherosclerosis

Silvio Buscemi, Giovam Battista Rini, Giuseppe Grosso, Giuseppe Lucisano, Luisella Cianferotti, Giuseppe Grosso, Fabio Galvano, Silvia Migliaccio, Antonio Nicolucci, Maria Luisa Brandi, Delia Sprini

Risultato della ricerca: Articlepeer review

15 Citazioni (Scopus)

Abstract

Background: Fish consumption is recommended as part of a healthy diet. However, there is a paucity of dataconcerning the relation between fish consumption and carotid atherosclerosis. We investigated the associationbetween habitual fish consumption and asymptomatic carotid atherosclerosis, defined as the presence of plaquesand/or increased intima-media thickness (≥ 0.90 mm), in non-diabetic participants.Methods: Nine hundred-sixty-one (range of age: 18–89 yrs; 37.1% males) adult participants without clinically knownatherosclerotic disease were randomly recruited among the customers of a shopping mall in Palermo, Italy, andcross-sectionally investigated. Each participant answered a food frequency questionnaire and underwenthigh-resolution ultrasonographic evaluation of both carotid arteries. Routine laboratory blood measurements wereobtained in a subsample of 507 participants.Results: Based on habitual fish consumption, participants were divided into three groups: non-consumers orconsumers of less than 1 serving a week (24.0%), consumers of 1 serving a week (38.8%), and consumers of ≥ 2servings a week (37.2%). Age-adjusted prevalence of carotid atherosclerosis (presence of plaques or intima mediathickness ≥ 0.9 mm) was higher in the low fish consumption group (13.3%, 12.1% and 6.6%, respectively; P = 0.003).Multivariate analysis evidenced that carotid atherosclerosis was significantly associated with age (OR = 1.12; 95%CI = 1.09-1.14), hypertension on pharmacologic treatment (OR = 1.81; 95% CI = 1.16-2.82), and pulse pressure(OR = 1.03; 95% CI = 1.01-1.04), while consuming ≥2 servings of fish weekly was protective compared with thecondition of consumption of <1 serving of fish weekly (OR = 0.46; 95% CI = 0.26-0.80).Conclusions: High habitual fish consumption seems to be associated with less carotid atherosclerosis, thoughadequate interventional trials are necessary to confirm the role of fish consumption in prevention of cardiovascular disease.
Lingua originaleEnglish
pagine (da-a)1-8
Numero di pagine8
RivistaNutrition Journal
Volume13
Stato di pubblicazionePublished - 2014

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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