Background: Fish consumption is recommended as part of a healthy diet. However, there is a paucity of dataconcerning the relation between fish consumption and carotid atherosclerosis. We investigated the associationbetween habitual fish consumption and asymptomatic carotid atherosclerosis, defined as the presence of plaquesand/or increased intima-media thickness (≥ 0.90 mm), in non-diabetic participants.Methods: Nine hundred-sixty-one (range of age: 18–89 yrs; 37.1% males) adult participants without clinically knownatherosclerotic disease were randomly recruited among the customers of a shopping mall in Palermo, Italy, andcross-sectionally investigated. Each participant answered a food frequency questionnaire and underwenthigh-resolution ultrasonographic evaluation of both carotid arteries. Routine laboratory blood measurements wereobtained in a subsample of 507 participants.Results: Based on habitual fish consumption, participants were divided into three groups: non-consumers orconsumers of less than 1 serving a week (24.0%), consumers of 1 serving a week (38.8%), and consumers of ≥ 2servings a week (37.2%). Age-adjusted prevalence of carotid atherosclerosis (presence of plaques or intima mediathickness ≥ 0.9 mm) was higher in the low fish consumption group (13.3%, 12.1% and 6.6%, respectively; P = 0.003).Multivariate analysis evidenced that carotid atherosclerosis was significantly associated with age (OR = 1.12; 95%CI = 1.09-1.14), hypertension on pharmacologic treatment (OR = 1.81; 95% CI = 1.16-2.82), and pulse pressure(OR = 1.03; 95% CI = 1.01-1.04), while consuming ≥2 servings of fish weekly was protective compared with thecondition of consumption of <1 serving of fish weekly (OR = 0.46; 95% CI = 0.26-0.80).Conclusions: High habitual fish consumption seems to be associated with less carotid atherosclerosis, thoughadequate interventional trials are necessary to confirm the role of fish consumption in prevention of cardiovascular disease.
|Numero di pagine||8|
|Stato di pubblicazione||Published - 2014|
All Science Journal Classification (ASJC) codes
- Medicine (miscellaneous)
- Nutrition and Dietetics