Graphene Oxide Carboxymethylcellulose Nanocomposite for Dressing Materials

Patrizia Cancemi, Maria Luisa Saladino, Rosa Alduina, Alessandro Presentato, Roberto Scaffaro, Marta Markowska, Magdalena Wawrzyńska, Dariusz Biały, Mariusz Hasiak, Dariusz Hreniak, Clara Carmone

Risultato della ricerca: Articlepeer review

11 Citazioni (Scopus)

Abstract

Sore, infected wounds are a major clinical issue, and there is thus an urgent need for novel biomaterials as multifunctional constituents for dressings. A set of biocomposites was prepared by solvent casting using different concentrations of carboxymethylcellulose (CMC) and exfoliated graphene oxide (Exf-GO) as a filler. Exf-GO was first obtained by the strong oxidation and exfoliation of graphite. The structural, morphological and mechanical properties of the composites (CMCx/Exf-GO) were evaluated, and the obtained composites were homogenous, transparent and brownish in color. The results confirmed that Exf-GO may be homogeneously dispersed in CMC. It was found that the composite has an inhibitory activity against the Gram-positive Staphylococcus aureus, but not against Gram-negative Pseudomonas aeruginosa. At the same time, it does not exhibit any cytotoxic effect on normal fibroblasts.
Lingua originaleEnglish
pagine (da-a)1980-
Numero di pagine14
RivistaMaterials
Volume13
Stato di pubblicazionePublished - 2020

All Science Journal Classification (ASJC) codes

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