TY - JOUR
T1 - Genotyping and antifungal susceptibility of Dipodascus capitatus isolated in a neonatal intensive care unit of a sicilian hospital
AU - Fasciana, Teresa Maria Assunta
AU - Corsello, Giovanni
AU - Giuffre, Mario
AU - Giammanco, Anna
AU - Cala', Cinzia
AU - Capra, Giuseppina
AU - Pinello, Giuseppa
AU - Schierz, Ingrid Anne Mandy
PY - 2017
Y1 - 2017
N2 - In August 2015, Dipodascus capitatus was isolated from two patients admitted to the neonatal intensive care unit. Nosocomial acquisition of the fungus was suspected and epidemiological studies were undertaken. The patients were simultaneously hospitalized, and the comparison of the two isolates by two independent molecular typing methods have confirmed clonal dissemination of a single strain of D. capitatus. Antimicrobial susceptibility testing was useful for identifying the appropriated antifungal therapy in micafungin. To our knowledge these are the first described cases of neonatal D. capitatus infection and also the first report of successful treatment by micafungin.
AB - In August 2015, Dipodascus capitatus was isolated from two patients admitted to the neonatal intensive care unit. Nosocomial acquisition of the fungus was suspected and epidemiological studies were undertaken. The patients were simultaneously hospitalized, and the comparison of the two isolates by two independent molecular typing methods have confirmed clonal dissemination of a single strain of D. capitatus. Antimicrobial susceptibility testing was useful for identifying the appropriated antifungal therapy in micafungin. To our knowledge these are the first described cases of neonatal D. capitatus infection and also the first report of successful treatment by micafungin.
KW - Antifungal Susceptibility; Dipodascus capitatus; Genotyping; Nosocomial Acquisition; Cross Infection; Dipodascus; Female; Genotype; Hospitals; Humans; Infant; Infant
KW - Genetics and Molecular Biology (all)
KW - Neonatal; Male; Mycoses; Sicily; Medicine (all); Biochemistry
KW - Newborn; Intensive Care Units
KW - Antifungal Susceptibility; Dipodascus capitatus; Genotyping; Nosocomial Acquisition; Cross Infection; Dipodascus; Female; Genotype; Hospitals; Humans; Infant; Infant
KW - Genetics and Molecular Biology (all)
KW - Neonatal; Male; Mycoses; Sicily; Medicine (all); Biochemistry
KW - Newborn; Intensive Care Units
UR - http://hdl.handle.net/10447/236759
UR - http://www.springer.com/series/5584
M3 - Article
SN - 0065-2598
VL - 973
SP - 81
EP - 88
JO - Advances in Experimental Medicine and Biology
JF - Advances in Experimental Medicine and Biology
ER -