Genetic characterization of G3 rotaviruses detected in Italian children in the years 1993–2005

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Abstract

In recent years an apparent increase in thefrequency of detection of G3P[8] rotaviruses has been observed worldwide. Similarly, in Italy G3P[8] strains have been detected sporadically and in a scattered fashion over 20 years, whereas in 2003 and 2005 G3P[8] rotavirus activity increased markedly. By analysis of the VP7, VP4, VP6, and NSP4 genes of a selection of G3P[8] rotaviruses detected between 1993 and 2005, a remarkable sequence conservation was observed in the VP7, VP4, and VP6 genes. By converse, after 2002 the Italian G3P[8] strains were found topossess unique mutations in significant regions of the NSP4 protein.
Lingua originaleEnglish
pagine (da-a)2089-2095
Numero di pagine7
RivistaJournal of Medical Virology
Volume81
Stato di pubblicazionePublished - 2009

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All Science Journal Classification (ASJC) codes

  • Virology
  • Infectious Diseases

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