Abstract
| Lingua originale | English |
|---|---|
| pagine (da-a) | 13-21 |
| Numero di pagine | 9 |
| Rivista | Journal of Sleep Research |
| Volume | 23 |
| Stato di pubblicazione | Published - 2014 |
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All Science Journal Classification (ASJC) codes
- Cognitive Neuroscience
- Behavioral Neuroscience
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Gender-specific anthropometric markers of adiposity, metabolic syndrome and visceral adiposity index (VAI) in patients with obstructive sleep apnea. / Battaglia, Salvatore; Bonsignore, Maria Rosaria; Esquinas, Cristina; Bonsignore, Maria R.; Marrone, Oreste; Barcelò, Antonia; Barbé, Ferran; Castrogiovanni, Alessandra; Marotta, Anna Maria; Mazzuca, Emilia.
In: Journal of Sleep Research, Vol. 23, 2014, pag. 13-21.Risultato della ricerca: Article
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TY - JOUR
T1 - Gender-specific anthropometric markers of adiposity, metabolic syndrome and visceral adiposity index (VAI) in patients with obstructive sleep apnea
AU - Battaglia, Salvatore
AU - Bonsignore, Maria Rosaria
AU - Esquinas, Cristina
AU - Bonsignore, Maria R.
AU - Marrone, Oreste
AU - Barcelò, Antonia
AU - Barbé, Ferran
AU - Castrogiovanni, Alessandra
AU - Marotta, Anna Maria
AU - Mazzuca, Emilia
PY - 2014
Y1 - 2014
N2 - Obstructive sleep apnea often coexists with visceral adiposity and metabolic syndrome. In this study, we analysed gender-related differences in anthropometrics according to sleep apnea severity and metabolic abnormalities. In addition, the visceral adiposity index, a recently introduced marker of cardiometabolic risk, was analysed. Consecutive subjects with suspected obstructive sleep apnea (n = 528, 423 males, mean age ± standard deviation: 51.3 ± 12.8 years, body mass index: 31.0 ± 6.2 kg m(-2) ) were studied by full polysomnography (apnea-hypopnea index 43.4 ± 27.6 h(-1) ). Variables of general and visceral adiposity were measured (body mass index, neck, waist and hip circumferences, waist-to-hip ratio). The visceral adiposity index was calculated, and metabolic syndrome was assessed (NCEP-ATP III criteria). The sample included controls (apnea-hypopnea index <10 h(-1) , n = 55), and patients with mild-moderate (apnea-hypopnea index 10-30 h(-1) , n = 144) and severe sleep apnea (apnea-hypopnea index >30 h(-1) , n = 329). When anthropometric variables were entered in stepwise multiple regression, body mass index, waist circumference and diagnosis of metabolic syndrome were associated with the apnea-hypopnea index in men (adjusted R(2) = 0.308); by contrast, only hip circumference and height-normalized neck circumference were associated with sleep apnea severity in women (adjusted R(2) = 0.339). These results changed little in patients without metabolic syndrome; conversely, waist circumference was the only correlate of apnea-hypopnea index in men and women with metabolic syndrome. The visceral adiposity index increased with insulin resistance, but did not predict sleep apnea severity. These data suggest gender-related interactions between obstructive sleep apnea, obesity and metabolic abnormalities. The visceral adiposity index was a good marker of metabolic syndrome, but not of obstructive sleep apnea.
AB - Obstructive sleep apnea often coexists with visceral adiposity and metabolic syndrome. In this study, we analysed gender-related differences in anthropometrics according to sleep apnea severity and metabolic abnormalities. In addition, the visceral adiposity index, a recently introduced marker of cardiometabolic risk, was analysed. Consecutive subjects with suspected obstructive sleep apnea (n = 528, 423 males, mean age ± standard deviation: 51.3 ± 12.8 years, body mass index: 31.0 ± 6.2 kg m(-2) ) were studied by full polysomnography (apnea-hypopnea index 43.4 ± 27.6 h(-1) ). Variables of general and visceral adiposity were measured (body mass index, neck, waist and hip circumferences, waist-to-hip ratio). The visceral adiposity index was calculated, and metabolic syndrome was assessed (NCEP-ATP III criteria). The sample included controls (apnea-hypopnea index <10 h(-1) , n = 55), and patients with mild-moderate (apnea-hypopnea index 10-30 h(-1) , n = 144) and severe sleep apnea (apnea-hypopnea index >30 h(-1) , n = 329). When anthropometric variables were entered in stepwise multiple regression, body mass index, waist circumference and diagnosis of metabolic syndrome were associated with the apnea-hypopnea index in men (adjusted R(2) = 0.308); by contrast, only hip circumference and height-normalized neck circumference were associated with sleep apnea severity in women (adjusted R(2) = 0.339). These results changed little in patients without metabolic syndrome; conversely, waist circumference was the only correlate of apnea-hypopnea index in men and women with metabolic syndrome. The visceral adiposity index increased with insulin resistance, but did not predict sleep apnea severity. These data suggest gender-related interactions between obstructive sleep apnea, obesity and metabolic abnormalities. The visceral adiposity index was a good marker of metabolic syndrome, but not of obstructive sleep apnea.
UR - http://hdl.handle.net/10447/97186
UR - http://onlinelibrary.wiley.com/store/10.1111/jsr.12088/asset/jsr12088.pdf?v=1&t=huvd0rrr&s=c4e40cb9aec74e889648171a9f1e6eb3e78f5404
M3 - Article
VL - 23
SP - 13
EP - 21
JO - Journal of Sleep Research
JF - Journal of Sleep Research
SN - 0962-1105
ER -