Functional variants of 5S rRNA in the ribosomes of common sea urchin Paracentrotus lividus

Fabio Caradonna, Daniele Bellavia

Risultato della ricerca: Article

14 Citazioni (Scopus)

Abstract

We have previously reported amolecular and cytogenetic characterization of three different 5S rDNA clusters in the sea urchin Paracentrotus lividus; this study, performed at DNA level only, lends itself as starting point to verify that these clusters could contain transcribed genes, then, to demonstrate the presence of heterogeneity at functional RNA level, also. In the present work we report in P. lividus ribosomes the existence of several transcribed variants of the 5S rRNA and we associate all transcribed variants to the cluster to which belong. Our finding is the first demonstration of the presence of high heterogeneity in functional 5S rRNA molecules in animal ribosomes, a feature that had been considered a peculiarity of some plants.
Lingua originaleEnglish
pagine (da-a)21-25
Numero di pagine5
RivistaGene
Volume508
Stato di pubblicazionePublished - 2012

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Genetics

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