Focus sui non responder alla terapia di resincronizzazione cardiaca: orizzonti e prospettive

Antonino Mignano, Salvatore Novo, Egle Corrado, Salvatore Novo, Patrizia Carità, Giuseppe Coppola, Antonino Mignano, Angela Nogara, Massimo Verdecchia, Gianfranco Ciaramitaro, Antonio Curnis, Gianluca Pontone, Egle Corrado, Angela Nogara, Gianfranco Ciaramitaro, Patrizia Carita'

Risultato della ricerca: Article

Abstract

Cardiac resynchronization therapy (CRT) has been shown as a successful strategy in the treatment of patients with heart failure and electrical dyssincrony. However, a significant proportion of implanted patients fails to respond sufficiently or in a predictable manner. Consequently, non response to CRT remains a valuable problem in clinical practice. In order to improve CRT response and long-term clinical benefits, the proper evaluation of patient's global frialty, the technology improvement, the multimodality imaging approach and the use of simple and low cost electrographic parameters (to verify effective biventricular capture and QRS narrowing) could play a important role. Therefore, the integration of various medical expertises (clinical cardiology, cardiac advanced imaging, electrophysiology) is a crucial element in order to achive the maximal benefits from this promising tecnique. In the multistep process (from patients evaluation to results verification) the follow-up even from the earliest post implantation phase, should be managed with great attention having the potential for impact the prognosis. This brief review focus the problem of non responder to CRT, giving particular attention to the different variables that may play a role (comorbilities, improvement in the tecnology of device implantation, role of multimodality imaging and electrocardiographic parameters).
Lingua originaleItalian
pagine (da-a)18-26
Numero di pagine9
RivistaRECENTI PROGRESSI IN MEDICINA
Volume108
Stato di pubblicazionePublished - 2017

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cita questo

Focus sui non responder alla terapia di resincronizzazione cardiaca: orizzonti e prospettive. / Mignano, Antonino; Novo, Salvatore; Corrado, Egle; Novo, Salvatore; Carità, Patrizia; Coppola, Giuseppe; Mignano, Antonino; Nogara, Angela; Verdecchia, Massimo; Ciaramitaro, Gianfranco; Curnis, Antonio; Pontone, Gianluca; Corrado, Egle; Nogara, Angela; Ciaramitaro, Gianfranco; Carita', Patrizia.

In: RECENTI PROGRESSI IN MEDICINA, Vol. 108, 2017, pag. 18-26.

Risultato della ricerca: Article

Mignano, A, Novo, S, Corrado, E, Novo, S, Carità, P, Coppola, G, Mignano, A, Nogara, A, Verdecchia, M, Ciaramitaro, G, Curnis, A, Pontone, G, Corrado, E, Nogara, A, Ciaramitaro, G & Carita', P 2017, 'Focus sui non responder alla terapia di resincronizzazione cardiaca: orizzonti e prospettive', RECENTI PROGRESSI IN MEDICINA, vol. 108, pagg. 18-26.
Mignano, Antonino ; Novo, Salvatore ; Corrado, Egle ; Novo, Salvatore ; Carità, Patrizia ; Coppola, Giuseppe ; Mignano, Antonino ; Nogara, Angela ; Verdecchia, Massimo ; Ciaramitaro, Gianfranco ; Curnis, Antonio ; Pontone, Gianluca ; Corrado, Egle ; Nogara, Angela ; Ciaramitaro, Gianfranco ; Carita', Patrizia. / Focus sui non responder alla terapia di resincronizzazione cardiaca: orizzonti e prospettive. In: RECENTI PROGRESSI IN MEDICINA. 2017 ; Vol. 108. pagg. 18-26.
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abstract = "Cardiac resynchronization therapy (CRT) has been shown as a successful strategy in the treatment of patients with heart failure and electrical dyssincrony. However, a significant proportion of implanted patients fails to respond sufficiently or in a predictable manner. Consequently, non response to CRT remains a valuable problem in clinical practice. In order to improve CRT response and long-term clinical benefits, the proper evaluation of patient's global frialty, the technology improvement, the multimodality imaging approach and the use of simple and low cost electrographic parameters (to verify effective biventricular capture and QRS narrowing) could play a important role. Therefore, the integration of various medical expertises (clinical cardiology, cardiac advanced imaging, electrophysiology) is a crucial element in order to achive the maximal benefits from this promising tecnique. In the multistep process (from patients evaluation to results verification) the follow-up even from the earliest post implantation phase, should be managed with great attention having the potential for impact the prognosis. This brief review focus the problem of non responder to CRT, giving particular attention to the different variables that may play a role (comorbilities, improvement in the tecnology of device implantation, role of multimodality imaging and electrocardiographic parameters).",
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T1 - Focus sui non responder alla terapia di resincronizzazione cardiaca: orizzonti e prospettive

AU - Mignano, Antonino

AU - Novo, Salvatore

AU - Corrado, Egle

AU - Novo, Salvatore

AU - Carità, Patrizia

AU - Coppola, Giuseppe

AU - Mignano, Antonino

AU - Nogara, Angela

AU - Verdecchia, Massimo

AU - Ciaramitaro, Gianfranco

AU - Curnis, Antonio

AU - Pontone, Gianluca

AU - Corrado, Egle

AU - Nogara, Angela

AU - Ciaramitaro, Gianfranco

AU - Carita', Patrizia

PY - 2017

Y1 - 2017

N2 - Cardiac resynchronization therapy (CRT) has been shown as a successful strategy in the treatment of patients with heart failure and electrical dyssincrony. However, a significant proportion of implanted patients fails to respond sufficiently or in a predictable manner. Consequently, non response to CRT remains a valuable problem in clinical practice. In order to improve CRT response and long-term clinical benefits, the proper evaluation of patient's global frialty, the technology improvement, the multimodality imaging approach and the use of simple and low cost electrographic parameters (to verify effective biventricular capture and QRS narrowing) could play a important role. Therefore, the integration of various medical expertises (clinical cardiology, cardiac advanced imaging, electrophysiology) is a crucial element in order to achive the maximal benefits from this promising tecnique. In the multistep process (from patients evaluation to results verification) the follow-up even from the earliest post implantation phase, should be managed with great attention having the potential for impact the prognosis. This brief review focus the problem of non responder to CRT, giving particular attention to the different variables that may play a role (comorbilities, improvement in the tecnology of device implantation, role of multimodality imaging and electrocardiographic parameters).

AB - Cardiac resynchronization therapy (CRT) has been shown as a successful strategy in the treatment of patients with heart failure and electrical dyssincrony. However, a significant proportion of implanted patients fails to respond sufficiently or in a predictable manner. Consequently, non response to CRT remains a valuable problem in clinical practice. In order to improve CRT response and long-term clinical benefits, the proper evaluation of patient's global frialty, the technology improvement, the multimodality imaging approach and the use of simple and low cost electrographic parameters (to verify effective biventricular capture and QRS narrowing) could play a important role. Therefore, the integration of various medical expertises (clinical cardiology, cardiac advanced imaging, electrophysiology) is a crucial element in order to achive the maximal benefits from this promising tecnique. In the multistep process (from patients evaluation to results verification) the follow-up even from the earliest post implantation phase, should be managed with great attention having the potential for impact the prognosis. This brief review focus the problem of non responder to CRT, giving particular attention to the different variables that may play a role (comorbilities, improvement in the tecnology of device implantation, role of multimodality imaging and electrocardiographic parameters).

KW - Cardiac Resynchronization Therapy

KW - Cardiac resynchronization therapy

KW - Electrocardiography

KW - Heart Failure

KW - Heart failure

KW - Humans

KW - Medicine (all)

KW - Multimodal Imaging

KW - Non responder

KW - Prognosis

KW - Treatment Outcome

UR - http://hdl.handle.net/10447/328365

M3 - Article

VL - 108

SP - 18

EP - 26

JO - RECENTI PROGRESSI IN MEDICINA

JF - RECENTI PROGRESSI IN MEDICINA

SN - 0034-1193

ER -