TY - JOUR
T1 - Fast recovery with etanercept in patients affected by polymyalgia
rheumatica and decompensated diabetes: a case-series study
AU - Licata, Giuseppe
AU - Scaglione, Rosario
AU - Colomba, Daniela
AU - Calvo, Luigi
AU - Pistone, Giovanni
PY - 2009
Y1 - 2009
N2 - We enrolled nine consecutive patients affected by newly diagnosed
polymyalgia rheumatica and decompensated diabetes mellitus. All patients
were treated with etanercept (25 mg twice weekly) and prednisone and
were followed up to 1 year. At the sixth-month follow-up, etanercept and
prednisone were withdrawn. Patients were seen at regular intervals (days
0, 30, 60, 90, 150, 180) and the following variables determined:
erythrocytes sedimentation rate, C-reactive protein, fasting serum
glucose, pain measured by visual analog scale, and the Health Assessment
Questionnaire. Our results indicate that etanercept might have some
steroid-sparing effects, but controlled investigations are needed to
support etanercept use in clinical practice for this kind of patients.
AB - We enrolled nine consecutive patients affected by newly diagnosed
polymyalgia rheumatica and decompensated diabetes mellitus. All patients
were treated with etanercept (25 mg twice weekly) and prednisone and
were followed up to 1 year. At the sixth-month follow-up, etanercept and
prednisone were withdrawn. Patients were seen at regular intervals (days
0, 30, 60, 90, 150, 180) and the following variables determined:
erythrocytes sedimentation rate, C-reactive protein, fasting serum
glucose, pain measured by visual analog scale, and the Health Assessment
Questionnaire. Our results indicate that etanercept might have some
steroid-sparing effects, but controlled investigations are needed to
support etanercept use in clinical practice for this kind of patients.
KW - Biological therapy; Decompensated diabetes mellitus; Etanercept;
Polymyalgia rheumatica; Steroid therapy
UR - http://hdl.handle.net/10447/121165
M3 - Article
VL - 28
SP - 89
EP - 92
JO - Clinical Rheumatology
JF - Clinical Rheumatology
SN - 0770-3198
ER -