Abstract
| Lingua originale | English |
|---|---|
| Stato di pubblicazione | Published - 2009 |
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Exposure to cytotoxic concentrations of manganese and effects on development. / Roccheri, Maria Carmela; Bosco, Liana; Pinsino, Annalisa.
2009.Risultato della ricerca: Other contribution
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TY - GEN
T1 - Exposure to cytotoxic concentrations of manganese and effects on development
AU - Roccheri, Maria Carmela
AU - Bosco, Liana
AU - Pinsino, Annalisa
PY - 2009
Y1 - 2009
N2 - Manganese is one of the most abundant metals present in nature in trace amounts, which is accumulated and utilized by all forms of life. It plays a multitude of biological roles, but exposure of cells/organisms to high levels causes toxicity. In the marine environment, increasing concentrations of bio-available ions often result from anthropogenic activities, and, consequently, manganese represents a new emergent factor in environmental contamination. To study cyto-toxicity of manganese on development, we used an excellent model system as sea urchin embryos Paracentrotus lividus. In this work, we show results from two-dimensional gel electrophoresis (2DE) analysis that highlighted qualitative/quantitative patterns of protein spots differences in control and manganese-exposed embryos.
AB - Manganese is one of the most abundant metals present in nature in trace amounts, which is accumulated and utilized by all forms of life. It plays a multitude of biological roles, but exposure of cells/organisms to high levels causes toxicity. In the marine environment, increasing concentrations of bio-available ions often result from anthropogenic activities, and, consequently, manganese represents a new emergent factor in environmental contamination. To study cyto-toxicity of manganese on development, we used an excellent model system as sea urchin embryos Paracentrotus lividus. In this work, we show results from two-dimensional gel electrophoresis (2DE) analysis that highlighted qualitative/quantitative patterns of protein spots differences in control and manganese-exposed embryos.
KW - manganese
KW - sea urchin embryos
KW - two-dimensional protein patterns.
UR - http://hdl.handle.net/10447/60309
M3 - Other contribution
ER -