Exploring a regulatory role for mast cells: 'MCregs'?

Claudio Tripodo, Barbara Frossi, Giorgia Gri, Carlo Pucillo

Risultato della ricerca: Article

54 Citazioni (Scopus)

Abstract

Regulatory cells can mould the fate of the immune response by direct suppression of specific subsets of effector cells, or by redirecting effectors against invading pathogens and infected or neoplastic cells. These functions have been classically, although not exclusively, ascribed to different subsets of T cells. Recently, mast cells have been shown to regulate physiological and pathological immune responses, and thus to act at the interface between innate and adaptive immunity assuming different functions and behaviors at discrete stages of the immune response. Here, we focus on these poorly defined, and sometimes apparently conflicting, functions of mast cells.
Lingua originaleEnglish
Numero di pagine0
RivistaTrends in Immunology
Volume3
Stato di pubblicazionePublished - 2010

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

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