Evidence of autonomic dysregulation in otherwise healthy cancer caregivers: a possible link with health hazard.

Gaetana Di Fede, Massimo Pagani, Mara Malacarne, Daniela Bruno, Daniela Lucini, Silvia Beltrami, Paolo Pizzinelli, Elena Piazza

Risultato della ricerca: Articlepeer review

31 Citazioni (Scopus)

Abstract

Caregiving, an important component of cancer patient treatment, may set forth a cascade of stress responses such as sympatho-adrenal activation, immuno-humoral changes and an unhealthy lifestyle, which could be hazardous to caregivers' health. In this observational study, we addressed whether autonomic nervous system (ANS) regulation and perception of stress would be altered in a group of 58 health cancer caregivers as compared to 60 controls. We employed non invasive autoregressive spectral analysis of cardiovascular variabilities and ad hoc questionnaires. Caregivers show, in addition to signs of psychological involvement, a clear autonomic imbalance, suggestive of sympathetic predominance at rest and of a reduction of vagal cardiac regulation (overall gain of baroreflex -index alpha- was respectively of 17.5+/-1.5 versus 25.1+/-1.8 msec/mmHg, p<<0.02). These data suggest possible preventive strategies, based on tailored treatments aiming at a betterment of individual autonomic profile.
Lingua originaleEnglish
pagine (da-a)2437-2443
Numero di pagine7
RivistaEuropean Journal of Cancer
Volume44
Stato di pubblicazionePublished - 2008

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Fingerprint Entra nei temi di ricerca di 'Evidence of autonomic dysregulation in otherwise healthy cancer caregivers: a possible link with health hazard.'. Insieme formano una fingerprint unica.

Cita questo