Evaluation of left ventricular mass on cadmiumzinc- telluride imaging: Validation against cardiac magnetic resonance

Salvatore Novo, Alessia Pepe, Riccardo Liga, Serena Magro, Anna Sonia Petronio, Alessia Gimelli, Paolo Marzullo, Roberto Pedrinelli, Alessia Pepe, Serena Magro

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    Abstract

    Background. Single-photon emission computed tomography has shown relevant limitationsin the quantification of left ventricular (LV) mass. We sought to compare the estimates of LVmass on Cadmium-Zinc-Telluride (CZT) myocardial perfusion imaging (MPI) as compared tocardiac magnetic resonance (CMR).Methods and results. Twenty-five patients underwent MPI on a CZT camera and CMR on a1.5 T scanner within 12 ± 3 weeks. LV mass was quantified on CZT images using two softwares:4D-MSPECT (4DM) and Emory Cardiac Toolbox (ECTb). LV mass by CMR was quantifiedusing MASS software (Medis, Leiden, The Netherlands). LV mass values obtained with 4DM andECTb were highly reproducible [intraclass correlation coefficients .98 (95% CI .97-.99), and .98(95% CI 0.97-.99), respectively]. The mean LVM mass values were 151 ± 44 g on CMR,151 ± 43 g with 4DM(P 5 NS vs CMR), and 157 ± 42 g with ECTb (P < .001 vs CMR; P 5 .007vs 4DM) CZT images. There was an excellent correlation between LV mass values between CMRand both 4DM (R2 5 .95; P < .001) and ECTb (R2 5 .98; P < .001) with narrow limits ofagreement (2 13.6% to 1 13.4% for 4DM, and 2 5.6% to 1 14.1% for ECTb).Conclusions. The evaluation of LV mass is feasible on CZT images, showing excellentagreement with CMR. (J Nucl Cardiol 2017)
    Lingua originaleEnglish
    Numero di pagine7
    RivistaJournal of Nuclear Cardiology
    Stato di pubblicazionePublished - 2017

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    All Science Journal Classification (ASJC) codes

    • Radiology Nuclear Medicine and imaging
    • Cardiology and Cardiovascular Medicine

    Cita questo

    Novo, S., Pepe, A., Liga, R., Magro, S., Petronio, A. S., Gimelli, A., Marzullo, P., Pedrinelli, R., Pepe, A., & Magro, S. (2017). Evaluation of left ventricular mass on cadmiumzinc- telluride imaging: Validation against cardiac magnetic resonance. Journal of Nuclear Cardiology.