Evaluation of labial microvessels in Sjogren syndrome: A videocapillaroscopic study

Scardina Ga; Ruggieri A; Messina P

Risultato della ricerca: Article

2 Citazioni (Scopus)

Abstract

Sjögren's syndrome (SS) is a chronic autoimmune rheumatic disease characterized by a progressive lymphocytic infiltration of exocrine glands, especially salivary and lachrymal ones, leading to xerostomia, parotid gland enlargement, and xerophtalmia. SS may occur alone (primary) or in association with almost any of the autoimmune rheumatic diseases (secondary), the most frequent being rheumatoid arthritis. The aim of this study is to describe the capillaroscopic pattern of the labial mucosa in patients with SS. METHODS: A total of 20 patients affected by SS and 20 healthy controls were examined. The patients with conditions that compromise microcirculation, such as diabetes, hypertension, hyperlipidemia or some pharmacological treatments, were not included in the study. All the patients were non-smokers. Labial capillaroscopy has been used to investigate the features of microcirculation. Visibility, course, tortuosity, as well as the possible presence of microhemorrhage, the average calibre of the capillary loops and the number of visible capillary loops per square millimetre were evaluated for each patient. RESULTS: The results show evident alterations in the capillaries and a typical conformation of the labial microcirculation in SS patients. CONCLUSION: Labial microcirculation alterations occur in SS patients. The study of the microcirculation in autoimmune pathology such as SS could provide new understanding on the dynamics of the pathology and could help to complete the diagnosis.
Lingua originaleEnglish
pagine (da-a)273-279
Numero di pagine7
RivistaAnnals of Anatomy
Volume191
Stato di pubblicazionePublished - 2009

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Sjogren's Syndrome
Lip
Microvessels
Microcirculation
Rheumatic Diseases
Autoimmune Diseases
Microscopic Angioscopy
Exocrine Glands
Pathology
Xerostomia
Parotid Gland
Hyperlipidemias
Rheumatoid Arthritis
Mucous Membrane
Pharmacology
Hypertension

All Science Journal Classification (ASJC) codes

  • Developmental Biology
  • Anatomy

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Evaluation of labial microvessels in Sjogren syndrome: A videocapillaroscopic study. / Scardina Ga; Ruggieri A; Messina P.

In: Annals of Anatomy, Vol. 191, 2009, pag. 273-279.

Risultato della ricerca: Article

Scardina Ga; Ruggieri A; Messina P 2009, 'Evaluation of labial microvessels in Sjogren syndrome: A videocapillaroscopic study', Annals of Anatomy, vol. 191, pagg. 273-279.
Scardina Ga; Ruggieri A; Messina P. / Evaluation of labial microvessels in Sjogren syndrome: A videocapillaroscopic study. In: Annals of Anatomy. 2009 ; Vol. 191. pagg. 273-279.
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abstract = "Sj{\"o}gren's syndrome (SS) is a chronic autoimmune rheumatic disease characterized by a progressive lymphocytic infiltration of exocrine glands, especially salivary and lachrymal ones, leading to xerostomia, parotid gland enlargement, and xerophtalmia. SS may occur alone (primary) or in association with almost any of the autoimmune rheumatic diseases (secondary), the most frequent being rheumatoid arthritis. The aim of this study is to describe the capillaroscopic pattern of the labial mucosa in patients with SS. METHODS: A total of 20 patients affected by SS and 20 healthy controls were examined. The patients with conditions that compromise microcirculation, such as diabetes, hypertension, hyperlipidemia or some pharmacological treatments, were not included in the study. All the patients were non-smokers. Labial capillaroscopy has been used to investigate the features of microcirculation. Visibility, course, tortuosity, as well as the possible presence of microhemorrhage, the average calibre of the capillary loops and the number of visible capillary loops per square millimetre were evaluated for each patient. RESULTS: The results show evident alterations in the capillaries and a typical conformation of the labial microcirculation in SS patients. CONCLUSION: Labial microcirculation alterations occur in SS patients. The study of the microcirculation in autoimmune pathology such as SS could provide new understanding on the dynamics of the pathology and could help to complete the diagnosis.",
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AU - Scardina, Giuseppe Alessandro

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N2 - Sjögren's syndrome (SS) is a chronic autoimmune rheumatic disease characterized by a progressive lymphocytic infiltration of exocrine glands, especially salivary and lachrymal ones, leading to xerostomia, parotid gland enlargement, and xerophtalmia. SS may occur alone (primary) or in association with almost any of the autoimmune rheumatic diseases (secondary), the most frequent being rheumatoid arthritis. The aim of this study is to describe the capillaroscopic pattern of the labial mucosa in patients with SS. METHODS: A total of 20 patients affected by SS and 20 healthy controls were examined. The patients with conditions that compromise microcirculation, such as diabetes, hypertension, hyperlipidemia or some pharmacological treatments, were not included in the study. All the patients were non-smokers. Labial capillaroscopy has been used to investigate the features of microcirculation. Visibility, course, tortuosity, as well as the possible presence of microhemorrhage, the average calibre of the capillary loops and the number of visible capillary loops per square millimetre were evaluated for each patient. RESULTS: The results show evident alterations in the capillaries and a typical conformation of the labial microcirculation in SS patients. CONCLUSION: Labial microcirculation alterations occur in SS patients. The study of the microcirculation in autoimmune pathology such as SS could provide new understanding on the dynamics of the pathology and could help to complete the diagnosis.

AB - Sjögren's syndrome (SS) is a chronic autoimmune rheumatic disease characterized by a progressive lymphocytic infiltration of exocrine glands, especially salivary and lachrymal ones, leading to xerostomia, parotid gland enlargement, and xerophtalmia. SS may occur alone (primary) or in association with almost any of the autoimmune rheumatic diseases (secondary), the most frequent being rheumatoid arthritis. The aim of this study is to describe the capillaroscopic pattern of the labial mucosa in patients with SS. METHODS: A total of 20 patients affected by SS and 20 healthy controls were examined. The patients with conditions that compromise microcirculation, such as diabetes, hypertension, hyperlipidemia or some pharmacological treatments, were not included in the study. All the patients were non-smokers. Labial capillaroscopy has been used to investigate the features of microcirculation. Visibility, course, tortuosity, as well as the possible presence of microhemorrhage, the average calibre of the capillary loops and the number of visible capillary loops per square millimetre were evaluated for each patient. RESULTS: The results show evident alterations in the capillaries and a typical conformation of the labial microcirculation in SS patients. CONCLUSION: Labial microcirculation alterations occur in SS patients. The study of the microcirculation in autoimmune pathology such as SS could provide new understanding on the dynamics of the pathology and could help to complete the diagnosis.

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