Eutopic endometrium from women with endometriosis does not exhibit neurotrophic properties

Vito Chiantera, Sylvia Mechsner, Vito Chiantera, Julia Bartley, Maria Luisa Barcena De Arellano, Giuseppe F. Vercellino, Magdalena Staube, Matthias Blöchle, Frank Sacher, Julia Arnold, Achim Schneider

Risultato della ricerca: Article

17 Citazioni (Scopus)

Abstract

The role of neurotrophins in eutopic endometrium from endometriosis-patients was investigated in a prospective study using immunofluorescence-staining, Western blot and a neuronal growth assay. The nerve growth factor is expressed in primary endometrial cell culture from women with and without endometriosis. Western blot analysis of endometrial biopsies or uterine fluid from patients with and without endometriosis shows no difference in the neurotrophin expression. We could not find a difference between patients with and without endometriosis with regards to the neurite outgrowth of sensory ganglia when treated with conditioned cultured medium or uterine fluid. This result refutes the assumed neurotrophic properties of eutopic endometrium of patients with endometriosis. © 2012 Elsevier B.V.
Lingua originaleEnglish
pagine (da-a)49-55
Numero di pagine7
RivistaJournal of Neuroimmunology
Volume249
Stato di pubblicazionePublished - 2012

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Endometriosis
Endometrium
Nerve Growth Factors
Western Blotting
Sensory Ganglia
Primary Cell Culture
Nerve Growth Factor
Conditioned Culture Medium
Fluorescent Antibody Technique
Prospective Studies
Staining and Labeling
Biopsy
Growth

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Clinical Neurology
  • Neurology
  • Immunology

Cita questo

Chiantera, V., Mechsner, S., Chiantera, V., Bartley, J., Barcena De Arellano, M. L., Vercellino, G. F., ... Schneider, A. (2012). Eutopic endometrium from women with endometriosis does not exhibit neurotrophic properties. Journal of Neuroimmunology, 249, 49-55.

Eutopic endometrium from women with endometriosis does not exhibit neurotrophic properties. / Chiantera, Vito; Mechsner, Sylvia; Chiantera, Vito; Bartley, Julia; Barcena De Arellano, Maria Luisa; Vercellino, Giuseppe F.; Staube, Magdalena; Blöchle, Matthias; Sacher, Frank; Arnold, Julia; Schneider, Achim.

In: Journal of Neuroimmunology, Vol. 249, 2012, pag. 49-55.

Risultato della ricerca: Article

Chiantera, V, Mechsner, S, Chiantera, V, Bartley, J, Barcena De Arellano, ML, Vercellino, GF, Staube, M, Blöchle, M, Sacher, F, Arnold, J & Schneider, A 2012, 'Eutopic endometrium from women with endometriosis does not exhibit neurotrophic properties', Journal of Neuroimmunology, vol. 249, pagg. 49-55.
Chiantera V, Mechsner S, Chiantera V, Bartley J, Barcena De Arellano ML, Vercellino GF e altri. Eutopic endometrium from women with endometriosis does not exhibit neurotrophic properties. Journal of Neuroimmunology. 2012;249:49-55.
Chiantera, Vito ; Mechsner, Sylvia ; Chiantera, Vito ; Bartley, Julia ; Barcena De Arellano, Maria Luisa ; Vercellino, Giuseppe F. ; Staube, Magdalena ; Blöchle, Matthias ; Sacher, Frank ; Arnold, Julia ; Schneider, Achim. / Eutopic endometrium from women with endometriosis does not exhibit neurotrophic properties. In: Journal of Neuroimmunology. 2012 ; Vol. 249. pagg. 49-55.
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abstract = "The role of neurotrophins in eutopic endometrium from endometriosis-patients was investigated in a prospective study using immunofluorescence-staining, Western blot and a neuronal growth assay. The nerve growth factor is expressed in primary endometrial cell culture from women with and without endometriosis. Western blot analysis of endometrial biopsies or uterine fluid from patients with and without endometriosis shows no difference in the neurotrophin expression. We could not find a difference between patients with and without endometriosis with regards to the neurite outgrowth of sensory ganglia when treated with conditioned cultured medium or uterine fluid. This result refutes the assumed neurotrophic properties of eutopic endometrium of patients with endometriosis. {\circledC} 2012 Elsevier B.V.",
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AU - Mechsner, Sylvia

AU - Chiantera, Vito

AU - Bartley, Julia

AU - Barcena De Arellano, Maria Luisa

AU - Vercellino, Giuseppe F.

AU - Staube, Magdalena

AU - Blöchle, Matthias

AU - Sacher, Frank

AU - Arnold, Julia

AU - Schneider, Achim

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AB - The role of neurotrophins in eutopic endometrium from endometriosis-patients was investigated in a prospective study using immunofluorescence-staining, Western blot and a neuronal growth assay. The nerve growth factor is expressed in primary endometrial cell culture from women with and without endometriosis. Western blot analysis of endometrial biopsies or uterine fluid from patients with and without endometriosis shows no difference in the neurotrophin expression. We could not find a difference between patients with and without endometriosis with regards to the neurite outgrowth of sensory ganglia when treated with conditioned cultured medium or uterine fluid. This result refutes the assumed neurotrophic properties of eutopic endometrium of patients with endometriosis. © 2012 Elsevier B.V.

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M3 - Article

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JO - Journal of Neuroimmunology

JF - Journal of Neuroimmunology

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