Epidemiology of desquamative gingivitis: evaluation of 125 patients and review of the literature

Domenico Compilato, Rosario Guiglia, Giuseppina Campisi, Domenico Compilato, Gabriella Fierro, Lucio Lo Russo, Giuseppina Campisi, Nunzio Francesco Testa, Lorenzo Lo Muzio, Lorenzo Lo Muzio, Giuseppina Campisi, Rosario Guiglia

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50 Citazioni (Scopus)


BACKGROUND: Desquamative gingivitis (DG) is a descriptive term used to indicate epithelial desquamation, erythema, erosions, and/or vesiculobullous lesions of the gingiva. DG is commonly associated with several mucocutaneous disorders and systemic conditions that may carry a poor prognosis and high morbidity; however, there are no clear data concerning the frequency of these disease associations. METHODS: We investigated the epidemiologic features of DG in 125 patients and compared our findings with information from a literature review. RESULTS: In our series, 88% of patients with DG had one of the following three disorders: oral lichen planus (OLP), mucous membrane pemphigoid (MMP), or pemphigus vulgaris. The most common cause of DG was OLP (75% of patients). 22% of patients had isolated gingival involvement, and there were diffuse gingival lesions in 57% of patients. Symptoms ranged from none (1%) to severe pain (10%). There was extra-oral involvement of skin in 14% of patients, conjunctiva in 7%, genital mucosa in 26%, and internal organs in 3%. Our study showed MMP to be associated with DG in only a small percentage of patients (9%); this finding may be related to the patient population, epidemiology of the specific disease, and referral and/or past diagnostic bias. CONCLUSION: Based on our series and recent reports, OLP seems to be the most common cause of DG.
Lingua originaleEnglish
pagine (da-a)1049-1052
Numero di pagine4
RivistaInternational Journal of Dermatology
Stato di pubblicazionePublished - 2009

All Science Journal Classification (ASJC) codes

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