Enteral Nutrition in Pancreaticoduodenectomy: A Literature Review

Antonio Marrazzo, Vincenzo Davide Palumbo, Attilio Ignazio Lo Monte, Salvatore Buscemi, Giuseppe Damiano, Giuseppe Damiano, Attilio I Lo Monte, Vincenzo D. Palumbo, Gabriele Spinelli, Silvia Ficarella

Risultato della ricerca: Articlepeer review

32 Citazioni (Scopus)


Pancreaticoduodenectomy (PD) is considered the gold standard treatment for periampullory carcinomas. This procedure presents 30%–40% of morbidity. Patients who have undergone pancreaticoduodenectomy often present perioperative malnutrition that is worse in the early postoperative days, affects the process of healing, the intestinal barrier function and the number of postoperative complications. Few studies focus on the relation between enteral nutrition (EN) and postoperative complications. Our aim was to perform a review, including only randomized controlled trial meta-analyses or well-designed studies, of evidence regarding the correlation between EN and main complications and outcomes after pancreaticoduodenectomy, as delayed gastric emptying (DGE), postoperative pancreatic fistula (POPF), postpancreatectomy hemorrhage (PPH), length of stay and infectious complications. Several studies, especially randomized controlled trial have shown that EN does not increase the rate of DGE. EN appeared safe and tolerated for patients after PD, even if it did not reveal any advantages in terms of POPF, PPH, length of stay and infectious complications.
Lingua originaleEnglish
pagine (da-a)3154-3165
Numero di pagine12
Stato di pubblicazionePublished - 2015

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.2900.2916???


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