Enhanced Lipid Peroxidation and Platelet Activation as Potential Contributors to Increased Cardiovascular Risk in the Low-HDL Phenotype

Maurizio Averna; Angelo Baldassare Cefalu'; Stefano Lattanzio; Natale Vazzana; Angelo Baldassare Cefalù; Nicole Santoro; Antonina Ganci; Davide Noto; Raoul Saggini; Luca Puccetti; Maurizio Averna; Giovanni Davì; Davide Noto

Enhanced Lipid Peroxidation and Platelet Activation as Potential Contributors to Increased Cardiovascular Risk in the Low-HDL Phenotype

Maurizio Averna, Angelo Baldassare Cefalu', Stefano Lattanzio, Natale Vazzana, Angelo Baldassare Cefalù, Nicole Santoro, Antonina Ganci, Davide Noto, Raoul Saggini, Luca Puccetti, Maurizio Averna, Giovanni Davì, Davide Noto

Promozione della Salute, Materno-Infantile, di Medicina Interna e Specialistica di Eccellenza “G. D’Alessandro”

Risultato della ricerca: Article › peer review

19 Citazioni (Scopus)

Abstract

Low high-density lipoprotein (HDL) levels are major predictors of cardiovascular (CV) events, even in patients on statin treatment with low-density lipoprotein (LDL) at target. In animal models HDLs protect LDL from oxidation and blunt platelet activation. Our study aimed to examine whether HDL levels are related to in vivo oxidative stress and platelet activation, as determinants of atherothrombosis.

Lingua originale	English
Numero di pagine	0
Rivista	JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE
Volume	2
Stato di pubblicazione	Published - 2013

All Science Journal Classification (ASJC) codes

Cardiology and Cardiovascular Medicine

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Averna, M., Cefalu', A. B., Lattanzio, S., Vazzana, N., Cefalù, A. B., Santoro, N., Ganci, A., Noto, D., Saggini, R., Puccetti, L., Averna, M., Davì, G., & Noto, D. (2013). Enhanced Lipid Peroxidation and Platelet Activation as Potential Contributors to Increased Cardiovascular Risk in the Low-HDL Phenotype. JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE, 2.

Enhanced Lipid Peroxidation and Platelet Activation as Potential Contributors to Increased Cardiovascular Risk in the Low-HDL Phenotype. / Averna, Maurizio ; Cefalu', Angelo Baldassare; Lattanzio, Stefano; Vazzana, Natale; Cefalù, Angelo Baldassare; Santoro, Nicole; Ganci, Antonina; Noto, Davide; Saggini, Raoul; Puccetti, Luca; Averna, Maurizio; Davì, Giovanni; Noto, Davide.

In: JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE, Vol. 2, 2013.

Risultato della ricerca: Article › peer review

Averna, M , Cefalu', AB, Lattanzio, S, Vazzana, N, Cefalù, AB, Santoro, N, Ganci, A, Noto, D, Saggini, R, Puccetti, L, Averna, M, Davì, G & Noto, D 2013, 'Enhanced Lipid Peroxidation and Platelet Activation as Potential Contributors to Increased Cardiovascular Risk in the Low-HDL Phenotype', JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE, vol. 2.

Averna, Maurizio ; Cefalu', Angelo Baldassare ; Lattanzio, Stefano ; Vazzana, Natale ; Cefalù, Angelo Baldassare ; Santoro, Nicole ; Ganci, Antonina ; Noto, Davide ; Saggini, Raoul ; Puccetti, Luca ; Averna, Maurizio ; Davì, Giovanni ; Noto, Davide. / Enhanced Lipid Peroxidation and Platelet Activation as Potential Contributors to Increased Cardiovascular Risk in the Low-HDL Phenotype. In: JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE. 2013 ; Vol. 2.

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abstract = "Low high-density lipoprotein (HDL) levels are major predictors of cardiovascular (CV) events, even in patients on statin treatment with low-density lipoprotein (LDL) at target. In animal models HDLs protect LDL from oxidation and blunt platelet activation. Our study aimed to examine whether HDL levels are related to in vivo oxidative stress and platelet activation, as determinants of atherothrombosis.",

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AU - Averna, Maurizio

AU - Cefalu', Angelo Baldassare

AU - Lattanzio, Stefano

AU - Vazzana, Natale

AU - Cefalù, Angelo Baldassare

AU - Santoro, Nicole

AU - Ganci, Antonina

AU - Noto, Davide

AU - Saggini, Raoul

AU - Puccetti, Luca

AU - Averna, Maurizio

AU - Davì, Giovanni

AU - Noto, Davide

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AB - Low high-density lipoprotein (HDL) levels are major predictors of cardiovascular (CV) events, even in patients on statin treatment with low-density lipoprotein (LDL) at target. In animal models HDLs protect LDL from oxidation and blunt platelet activation. Our study aimed to examine whether HDL levels are related to in vivo oxidative stress and platelet activation, as determinants of atherothrombosis.

UR - http://hdl.handle.net/10447/73835

M3 - Article

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JO - Journal of the American Heart Association

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