Enhanced Lipid Peroxidation and Platelet Activation as Potential Contributors to Increased Cardiovascular Risk in the Low-HDL Phenotype

Maurizio Averna, Angelo Baldassare Cefalu', Stefano Lattanzio, Natale Vazzana, Angelo Baldassare Cefalù, Nicole Santoro, Antonina Ganci, Davide Noto, Raoul Saggini, Luca Puccetti, Maurizio Averna, Giovanni Davì, Davide Noto

Risultato della ricerca: Articlepeer review

19 Citazioni (Scopus)

Abstract

Low high-density lipoprotein (HDL) levels are major predictors of cardiovascular (CV) events, even in patients on statin treatment with low-density lipoprotein (LDL) at target. In animal models HDLs protect LDL from oxidation and blunt platelet activation. Our study aimed to examine whether HDL levels are related to in vivo oxidative stress and platelet activation, as determinants of atherothrombosis.
Lingua originaleEnglish
Numero di pagine0
RivistaJOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE
Volume2
Stato di pubblicazionePublished - 2013

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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